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NCT00975767 · ClinicalTrials.gov registry record · Phase 1

A Study of MGCD265 Given With Erlotinib or Docetaxel in Subjects With Advanced Malignancies or Non-Small Cell Lung Cancer

A Phase 1 study, sponsored by Mirati Therapeutics.

Terminated
Registry status
Phase 1
Development phase
126
Enrollment target

NCT00975767: Clinical Trial Phase 1 study, sponsored by Mirati Therapeutics.

NCT00975767 is a Phase 1 study that was terminated before completion, run by Mirati Therapeutics. The registered enrollment target is 126 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (110% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00975767, a Phase 1 study, was terminated before completion, sponsored by Mirati Therapeutics.

TERMINATED
Registry status
Phase 1
Development phase
126 participants
Enrollment target

Study Summary

The main purpose of this study is to assess the safety profile of MGCD265 when administered in combination with the marketed anticancer drugs erlotinib and docetaxel.

Interventions

  • DRUG MGCD265+erlotinib
  • DRUG MGCD265+docetaxel

Trial Details

FieldValue
Enrollment Target 126 participants
Start Date 2009-08
Est. Completion 2014-08
Phase Phase 1
Mirati Therapeutics

49 total trials

Why NCT00975767 stopped before completion

NCT00975767 is an interventional study that assigns participants to a tested intervention. The registered 126 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (110% higher).

The record links to 0 conditions, and to 2 interventions - of which MGCD265+erlotinib is the first listed.

NCT00975767 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00975767 about?

NCT00975767 is a clinical study titled "A Study of MGCD265 Given With Erlotinib or Docetaxel in Subjects With Advanced Malignancies or Non-Small Cell Lung Cancer". The main purpose of this study is to assess the safety profile of MGCD265 when administered in combination with the marketed anticancer drugs erlotinib and docetaxel.

What is the current status of trial NCT00975767?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 126 participants. The study started on 2009-08. Estimated completion is 2014-08.

What interventions are being tested in trial NCT00975767?

The interventions under investigation include: MGCD265+erlotinib (DRUG), MGCD265+docetaxel (DRUG).

Who is sponsoring clinical trial NCT00975767?

This trial is sponsored by Mirati Therapeutics, which has 49 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00975767's enrollment target sits among peer trials

126 461st of 2000 higher than 1,534 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00975767, the US trial registry maintained by the National Library of Medicine. NCT00975767 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.