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NCT00970905 · ClinicalTrials.gov registry record · Phase 2

Effectiveness of Aprepitant in Addition to Ondansetron in the Prevention of Nausea and Vomiting Caused by Upper Abdominal Radiotherapy

A Phase 2 study, sponsored by University of Vermont.

Completed
Registry status
Phase 2
Development phase
52
Enrollment target

NCT00970905 is a Phase 2 study that has completed, run by University of Vermont. The registered enrollment target is 52 participants.

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The verdict

NCT00970905, a Phase 2 study, has completed, sponsored by University of Vermont.

COMPLETED
Registry status
Phase 2
Development phase
52 participants
Enrollment target

Study Summary

Severe nausea and/or vomiting in patients receiving radiotherapy to the upper abdomen is common despite having received pre-medication with ondansetron, a standard preventive treatment. This study aims to reduce the incidence of significant nausea and/or vomiting with the addition of the NK1-antagonist aprepitant to standard ondansetron treatment. This study will also assess the safety and tolerability of prolonged administration of aprepitant over the 4 to 6 week period of radiation treatment.

Interventions

  • DRUG Ondansetron
  • DRUG aprepitant

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2009-10
Est. Completion 2016-08-01
Phase Phase 2

Sponsor

University of Vermont

162 total trials

What the Registry Record Tells You About NCT00970905

The ClinicalTrials.gov registry entry for NCT00970905 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 52 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Vermont, which has 162 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Ondansetron is the first listed.

NCT00970905 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00970905 about?

NCT00970905 is a clinical study titled "Effectiveness of Aprepitant in Addition to Ondansetron in the Prevention of Nausea and Vomiting Caused by Upper Abdominal Radiotherapy". Severe nausea and/or vomiting in patients receiving radiotherapy to the upper abdomen is common despite having received pre-medication with ondansetron, a standard preventive treatment. This study aims to reduce the incidence of significant nausea and/or vomiting with the addition of the NK1-antagon...

What is the current status of trial NCT00970905?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 52 participants. The study started on 2009-10. Estimated completion is 2016-08-01.

What interventions are being tested in trial NCT00970905?

The interventions under investigation include: Ondansetron (DRUG), aprepitant (DRUG).

Who is sponsoring clinical trial NCT00970905?

This trial is sponsored by University of Vermont, which has 162 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.