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NCT00964678 · ClinicalTrials.gov registry record · Phase 1
Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension
A Phase 1 study, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
NCT00964678: Completed Phase 1 study, sponsored by Virginia Commonwealth University.
NCT00964678 is a Phase 1 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 10 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00964678, a Phase 1 study, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether carvedilol treatment of patients with pulmonary arterial hypertension and associated right heart failure is safe and results in an improved function of the right heart.
Primary Outcome
Change in right ventricular ejection fraction is measured by cardiac magnetic resonance imaging, using the method of disks with the reading radiologist being blinded to before and after images. Cardiac magnetic resonance imaging was done at baseline and 6 months only
Interventions
- DRUG Carvedilol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2010-06 |
| Est. Completion | 2014-05 |
| Phase | Phase 1 |
What the finished NCT00964678 record still lists
NCT00964678 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (83% lower).
The record links to 0 conditions, and to 1 intervention - of which Carvedilol is the first listed.
NCT00964678 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00964678 about?
NCT00964678 is a clinical study titled "Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial Hypertension". The purpose of this study is to determine whether carvedilol treatment of patients with pulmonary arterial hypertension and associated right heart failure is safe and results in an improved function of the right heart.
What is the current status of trial NCT00964678?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2010-06. Estimated completion is 2014-05.
What interventions are being tested in trial NCT00964678?
The interventions under investigation include: Carvedilol (DRUG).
Who is sponsoring clinical trial NCT00964678?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00964678's enrollment target sits among peer trials
10 1913th of 2000 higher than 46 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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