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NCT00956904 · ClinicalTrials.gov registry record · Early Phase 1

Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy

A Early Phase 1 study, sponsored by Johns Hopkins University.

Terminated
Registry status
Early Phase 1
Development phase
50
Enrollment target

NCT00956904: Clinical Trial Early Phase 1 study, sponsored by Johns Hopkins University.

NCT00956904 is a Early Phase 1 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 50 participants, roughly in line with the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00956904, a Early Phase 1 study, was terminated before completion, sponsored by Johns Hopkins University.

TERMINATED
Registry status
Early Phase 1
Development phase
50 participants
Enrollment target

Study Summary

A new solution for guiding the surgeon in robot-assisted laparoscopic radical prostatectomy (RALP) is image-guided navigation using transrectal ultrasound (TRUS). A TRUS-guided intraoperative navigation system using a robotic ultrasound probe manipulator (TRUS Robot) has been developed. The proposed research is a pilot clinical trial of the TRUS Robot and three-dimensional (3-D) navigation software to test its image-guidance ability of helping the surgeon during RALP. This is a dual robot approach, a Tandem-RALP (T-RALP). The TRUS Robot allows a steady holding as well as remote manipulation of the TRUS probe. In addition, the TRUS Robot can track the accurate position of TRUS probe which allows 3-D reconstruction of the images. While the intraoperative TRUS findings will not be used in surgical decision making in this trial, the use of TRUS imaging during radical prostatectomy can potentially improve the visualization of the NVB and subsequently improve postoperative recovery of potency in men. In addition, the 3-D reconstruction images of the prostate gland can potentially provide clear and accurate guidance of surgical landmarks to the surgeon..

Primary Outcome

To assess whether NVB localization is accurate using the TRUS Robot and 3-D TRUS navigation software during T-RALP \& can accurately locate and quantify the distance between anatomical landmarks.

Interventions

  • DEVICE 3-D TRUS navigation software during T-RALP

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2009-08
Est. Completion 2013-06
Phase Early Phase 1
Johns Hopkins University

1,448 total trials

Why NCT00956904 stopped before completion

NCT00956904 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, roughly in line with the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target.

The record links to 0 conditions, and to 1 intervention - of which 3-D TRUS navigation software during T-RALP is the first listed.

NCT00956904 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00956904 about?

NCT00956904 is a clinical study titled "Ultrasound-Guided Navigation in Robot-Assisted Laparoscopic Radical Prostatectomy". A new solution for guiding the surgeon in robot-assisted laparoscopic radical prostatectomy (RALP) is image-guided navigation using transrectal ultrasound (TRUS). A TRUS-guided intraoperative navigation system using a robotic ultrasound probe manipulator (TRUS Robot) has been developed. The proposed...

What is the current status of trial NCT00956904?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 50 participants. The study started on 2009-08. Estimated completion is 2013-06.

What interventions are being tested in trial NCT00956904?

The interventions under investigation include: 3-D TRUS navigation software during T-RALP (DEVICE).

Who is sponsoring clinical trial NCT00956904?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00956904's enrollment target sits among peer trials

50 493rd of 2000 higher than 1,467 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00956904, the US trial registry maintained by the National Library of Medicine. NCT00956904 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.