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NCT00956020 · ClinicalTrials.gov registry record · Phase 1
Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation
A Phase 1 study, sponsored by The New York Eye & Ear Infirmary.
- Completed
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT00956020: Completed Phase 1 study, sponsored by The New York Eye & Ear Infirmary.
NCT00956020 is a Phase 1 study that has completed, run by The New York Eye & Ear Infirmary. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00956020, a Phase 1 study, has completed, sponsored by The New York Eye & Ear Infirmary.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues. This study is designed to evaluate the histologic and biochemical effect of injection of platelet rich fibrin matrix into the skin.
Primary Outcome
Biopsy specimen will be obtained from PRFM treated skin, sectioned and stained with H\&E. Qualitative differences from standard laboratory control specimen of normal untreated skin (not obtained from study participants) in dermal and sub dermal collagen (as determined by the number of specimen which had greater than 25% new collagen deposition per high powered field) 30 minutes after treatment with platelet rich fibrin matrix will be reported. The results were characterize the general qualitativ
Interventions
- BIOLOGICAL Platelet rich fibrin matrix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2009-10 |
| Est. Completion | 2011-07 |
| Phase | Phase 1 |
What the finished NCT00956020 record still lists
NCT00956020 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 1 intervention - of which Platelet rich fibrin matrix is the first listed.
NCT00956020 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00956020 about?
NCT00956020 is a clinical study titled "Evaluation of the Mechanism of Action of Platelet Rich Fibrin Matrix (PRFM) in Producing Skin Volume Augmentation". Autologous platelet rich fibrin matrix will release growth factors which could increase the production of dermal proteins or affect the vascularity and status of neighboring tissues. This study is designed to evaluate the histologic and biochemical effect of injection of platelet rich fibrin matrix ...
What is the current status of trial NCT00956020?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2009-10. Estimated completion is 2011-07.
What interventions are being tested in trial NCT00956020?
The interventions under investigation include: Platelet rich fibrin matrix (BIOLOGICAL).
Who is sponsoring clinical trial NCT00956020?
This trial is sponsored by The New York Eye & Ear Infirmary, which has 12 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00956020's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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