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NCT00952289 · ClinicalTrials.gov registry record · Phase 3

COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial

A Phase 3 study, sponsored by Incyte Corporation.

Completed
Registry status
Phase 3
Development phase
309
Enrollment target

NCT00952289 is a Phase 3 study that has completed, run by Incyte Corporation. The registered enrollment target is 309 participants.

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The verdict

NCT00952289, a Phase 3 study, has completed, sponsored by Incyte Corporation.

COMPLETED
Registry status
Phase 3
Development phase
309 participants
Enrollment target

Study Summary

This was a randomized, double-blind study comparing the efficacy and safety of ruxolitinib (INCB018424) tablets to matching placebo tablets in patients diagnosed with Myelofibrosis (either Primary Myelofibrosis (PMF) or Post-Polycythemia Vera Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia Myelofibrosis (PET-MF).

Interventions

  • DRUG Placebo
  • DRUG Ruxolitinib

Trial Details

FieldValue
Enrollment Target 309 participants
Start Date 2009-08
Est. Completion 2015-10
Phase Phase 3

Sponsor

Incyte Corporation

239 total trials

What the Registry Record Tells You About NCT00952289

The ClinicalTrials.gov registry entry for NCT00952289 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 309 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Incyte Corporation, which has 239 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00952289 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00952289 about?

NCT00952289 is a clinical study titled "COntrolled MyeloFibrosis Study With ORal JAK Inhibitor Treatment: The COMFORT-I Trial". This was a randomized, double-blind study comparing the efficacy and safety of ruxolitinib (INCB018424) tablets to matching placebo tablets in patients diagnosed with Myelofibrosis (either Primary Myelofibrosis (PMF) or Post-Polycythemia Vera Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia ...

What is the current status of trial NCT00952289?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 309 participants. The study started on 2009-08. Estimated completion is 2015-10.

What interventions are being tested in trial NCT00952289?

The interventions under investigation include: Placebo (DRUG), Ruxolitinib (DRUG).

Who is sponsoring clinical trial NCT00952289?

This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.