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NCT00949624 · ClinicalTrials.gov registry record · Phase 1

CP-868,596 And CP-868,596 Plus AG-013736 In Combination With Docetaxel In Advanced Solid Tumors

A Phase 1 study, sponsored by Arog Pharmaceuticals.

Completed
Registry status
Phase 1
Development phase
50
Enrollment target

NCT00949624: Completed Phase 1 study, sponsored by Arog Pharmaceuticals.

NCT00949624 is a Phase 1 study that has completed, run by Arog Pharmaceuticals. The registered enrollment target is 50 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00949624, a Phase 1 study, has completed, sponsored by Arog Pharmaceuticals.

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target

Study Summary

A5301005 is a phase 1 study in patients with solid tumors which is testing the safety and tolerability of adding targeted agents to a standard chemotherapy. CP-868,596 is a platelet-derived growth factor receptor inhibitor (PDGFR) and AG-13736 is a vascular endothelial growth factor receptor inhibitor (VEGFR). This study will test the use of docetaxel (the standard chemotherapy) with either CP-868,596 or the combination of CP-868,596 and AG-13736.

Interventions

  • DRUG Docetaxel
  • DRUG CP-868,596

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2005-12
Est. Completion 2008-06
Phase Phase 1
Arog Pharmaceuticals

13 total trials

What the finished NCT00949624 record still lists

NCT00949624 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (17% lower).

The record links to 0 conditions, and to 2 interventions - of which Docetaxel is the first listed.

NCT00949624 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00949624 about?

NCT00949624 is a clinical study titled "CP-868,596 And CP-868,596 Plus AG-013736 In Combination With Docetaxel In Advanced Solid Tumors". A5301005 is a phase 1 study in patients with solid tumors which is testing the safety and tolerability of adding targeted agents to a standard chemotherapy. CP-868,596 is a platelet-derived growth factor receptor inhibitor (PDGFR) and AG-13736 is a vascular endothelial growth factor receptor inhibit...

What is the current status of trial NCT00949624?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. The study started on 2005-12. Estimated completion is 2008-06.

What interventions are being tested in trial NCT00949624?

The interventions under investigation include: Docetaxel (DRUG), CP-868,596 (DRUG).

Who is sponsoring clinical trial NCT00949624?

This trial is sponsored by Arog Pharmaceuticals, which has 13 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00949624's enrollment target sits among peer trials

50 973rd of 2000 higher than 984 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00949624, the US trial registry maintained by the National Library of Medicine. NCT00949624 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.