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NCT00946478 · ClinicalTrials.gov registry record · NA
Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema
A NA study, sponsored by University of California, San Diego.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT00946478: Completed NA study, sponsored by University of California, San Diego.
NCT00946478 is a NA study that has completed, run by University of California, San Diego. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00946478, a NA study, has completed, sponsored by University of California, San Diego.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effect of topical pimecrolimus on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with eczema. It is hypothesized that pimecrolimus applied topically will repair the body's immune system in patients with eczema by increasing antimicrobial peptides.
Primary Outcome
Delta-delta CT values were measured using RT-PCR of cathelicidin mRNA in human biopsy samples at baseline, and then 3 weeks after treatment with either pimecrolimus or placebo
Interventions
- DRUG Pimecrolimus
- OTHER Vehicle cream
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2009-10 |
| Est. Completion | 2011-05 |
| Phase | NA |
What the finished NCT00946478 record still lists
NCT00946478 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Pimecrolimus is the first listed.
NCT00946478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00946478 about?
NCT00946478 is a clinical study titled "Effect of Pimecrolimus Cream on Cathelicidin Levels in Subjects With Eczema". The purpose of this study is to determine the effect of topical pimecrolimus on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with eczema. It is hypothesized that pimecrolimus applied topically will repair the body's immune system in patients with eczema...
What is the current status of trial NCT00946478?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2009-10. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00946478?
The interventions under investigation include: Pimecrolimus (DRUG), Vehicle cream (OTHER).
Who is sponsoring clinical trial NCT00946478?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00946478's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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