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NCT00945269 · ClinicalTrials.gov registry record · Phase 1

Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma

A Phase 1 study, sponsored by Fred Hutchinson Cancer Center.

Terminated
Registry status
Phase 1
Development phase
3
Enrollment target

NCT00945269 is a Phase 1 study that was terminated before completion, run by Fred Hutchinson Cancer Center. The registered enrollment target is 3 participants.

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The verdict

NCT00945269, a Phase 1 study, was terminated before completion, sponsored by Fred Hutchinson Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
3 participants
Enrollment target

Study Summary

RATIONALE: White blood cells that have been treated in a laboratory may be able to kill tumor cells in patients with melanoma. Aldesleukin and denileukin diftitox may stimulate the white blood cells to kill melanoma cells. Giving therapeutic autologous lymphocyte therapy together with aldesleukin and denileukin diftitox may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects of giving therapeutic autologous lymphocytes together with aldesleukin and denileukin diftitox and to see how well it works in treating patients with stage III-IV melanoma

Interventions

  • PROCEDURE biopsy
  • OTHER immunohistochemistry staining method
  • BIOLOGICAL therapeutic autologous lymphocytes
  • BIOLOGICAL aldesleukin
  • BIOLOGICAL denileukin diftitox

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2009-07
Est. Completion 2011-01
Phase Phase 1

Sponsor

Fred Hutchinson Cancer Center

483 total trials

What the Registry Record Tells You About NCT00945269

The ClinicalTrials.gov registry entry for NCT00945269 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Fred Hutchinson Cancer Center, which has 483 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which biopsy is the first listed.

NCT00945269 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00945269 about?

NCT00945269 is a clinical study titled "Therapeutic Autologous Lymphocytes, Aldesleukin, and Denileukin Diftitox in Treating Patients With Stage III-IV Melanoma". RATIONALE: White blood cells that have been treated in a laboratory may be able to kill tumor cells in patients with melanoma. Aldesleukin and denileukin diftitox may stimulate the white blood cells to kill melanoma cells. Giving therapeutic autologous lymphocyte therapy together with aldesleukin an...

What is the current status of trial NCT00945269?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 2009-07. Estimated completion is 2011-01.

What interventions are being tested in trial NCT00945269?

The interventions under investigation include: biopsy (PROCEDURE), immunohistochemistry staining method (OTHER), therapeutic autologous lymphocytes (BIOLOGICAL), aldesleukin (BIOLOGICAL), denileukin diftitox (BIOLOGICAL).

Who is sponsoring clinical trial NCT00945269?

This trial is sponsored by Fred Hutchinson Cancer Center, which has 483 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.