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NCT00944229 · ClinicalTrials.gov registry record · Phase 3

The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure

A Phase 3 study, sponsored by Columbia University.

Terminated
Registry status
Phase 3
Development phase
58
Enrollment target

NCT00944229: Clinical Trial Phase 3 study, sponsored by Columbia University.

NCT00944229 is a Phase 3 study that was terminated before completion, run by Columbia University. The registered enrollment target is 58 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00944229, a Phase 3 study, was terminated before completion, sponsored by Columbia University.

TERMINATED
Registry status
Phase 3
Development phase
58 participants
Enrollment target

Study Summary

A diet rich in Omega-3 (fish oil) reduces plasma triglycerides and the risk for ischemic heart disease. Recently, a large trial evaluating treatment with Omega 3 in heart failure patients suggested that omega 3 may lower the risk of death from CHF. The mechanism of this potential benefit is not well understood. Methods: Forty patients will be enrolled in the study. Twenty patients will receive Omega 3 (lovaza 4 gm a day) and 20 patients will receive placebo. All subjects will have assessment of their exercise capacity and blood vessel function before and after an 8 week treatment period. About 4 table spoons of blood will be drawn throughout the study. Expected results: The investigators believe that omega 3 may improve the ability to exercise and improve blood vessel function.

Interventions

  • DRUG Placebo
  • DRUG LOVAZA (Omega-3)

Trial Details

FieldValue
Enrollment Target 58 participants
Start Date 2010-01
Est. Completion 2014-03
Phase Phase 3
Columbia University

958 total trials

Why NCT00944229 stopped before completion

NCT00944229 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 58 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (92% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00944229 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00944229 about?

NCT00944229 is a clinical study titled "The Effect of Omega-3 Polyunsaturated Fatty Acids in Congestive Heart Failure". A diet rich in Omega-3 (fish oil) reduces plasma triglycerides and the risk for ischemic heart disease. Recently, a large trial evaluating treatment with Omega 3 in heart failure patients suggested that omega 3 may lower the risk of death from CHF. The mechanism of this potential benefit is not well...

What is the current status of trial NCT00944229?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 58 participants. The study started on 2010-01. Estimated completion is 2014-03.

What interventions are being tested in trial NCT00944229?

The interventions under investigation include: Placebo (DRUG), LOVAZA (Omega-3) (DRUG).

Who is sponsoring clinical trial NCT00944229?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00944229's enrollment target sits among peer trials

58 1825th of 2000 higher than 174 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00944229, the US trial registry maintained by the National Library of Medicine. NCT00944229 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.