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NCT00943631 · ClinicalTrials.gov registry record · Phase 2

Sanofi H1N1 Influenza Vaccine Administered at Two Dose Levels in Adult and Elderly Populations

A Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 2
Development phase
406
Enrollment target

NCT00943631: Completed Phase 2 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00943631 is a Phase 2 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 406 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (205% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00943631, a Phase 2 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 2
Development phase
406 participants
Enrollment target

Study Summary

The purpose of this study is to assess the safety and the body's immune response (body's defense against disease) to an experimental H1N1 influenza vaccine in healthy adult and elderly populations. The study will enroll up to 450 healthy adults ages 18 and older with no history of H1N1 infection or vaccination. Two hundred individuals will be 18-64 years old, and the other 200 will be greater than or equal to 65 years of age. Participants will be randomly assigned to 1 of 2 possible vaccine groups: group 1 will receive 15 mcg of H1N1 vaccine; group 2 will receive 30 mcg of H1N1 vaccine. Both groups will receive vaccine injections on days 0 and 21 in the arm muscle. Study procedures include: medical history, physical exam, maintaining a memory aid, and blood sample collection. Participants will be involved in study related procedures for approximately 7 months.

Primary Outcome

Serious adverse events included any untoward medical occurrence that resulted in death; was life threatening; was a persistent/significant disability/incapacity; required in-patient hospitalization or prolongation thereof; resulted in a congenital anomaly/birth defect; or may have jeopardized the participant or required intervention to prevent one of these outcomes. Association to vaccination was determined by a study clinician licensed to make medical diagnoses.

Interventions

  • BIOLOGICAL Inactivated H1N1 Vaccine

Trial Details

FieldValue
Enrollment Target 406 participants
Start Date 2009-08
Est. Completion 2010-03
Phase Phase 2

What the finished NCT00943631 record still lists

NCT00943631 is an interventional study that assigns participants to a tested intervention. The registered 406 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (205% higher).

The record links to 0 conditions, and to 1 intervention - of which Inactivated H1N1 Vaccine is the first listed.

NCT00943631 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00943631 about?

NCT00943631 is a clinical study titled "Sanofi H1N1 Influenza Vaccine Administered at Two Dose Levels in Adult and Elderly Populations". The purpose of this study is to assess the safety and the body's immune response (body's defense against disease) to an experimental H1N1 influenza vaccine in healthy adult and elderly populations. The study will enroll up to 450 healthy adults ages 18 and older with no history of H1N1 infection or ...

What is the current status of trial NCT00943631?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 406 participants. The study started on 2009-08. Estimated completion is 2010-03.

What interventions are being tested in trial NCT00943631?

The interventions under investigation include: Inactivated H1N1 Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT00943631?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00943631's enrollment target sits among peer trials

406 94th of 2000 higher than 1,906 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00943631, the US trial registry maintained by the National Library of Medicine. NCT00943631 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.