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NCT00937105 · ClinicalTrials.gov registry record · Phase 4
Daily Wear Corneal Infiltrative Event Study
A Phase 4 study, sponsored by University Hospitals Cleveland Medical Center.
- Completed
- Registry status
- Phase 4
- Development phase
- 218
- Enrollment target
NCT00937105: Completed Phase 4 study, sponsored by University Hospitals Cleveland Medical Center.
NCT00937105 is a Phase 4 study that has completed, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 218 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00937105, a Phase 4 study, has completed, sponsored by University Hospitals Cleveland Medical Center.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 218 participants
- Enrollment target
Study Summary
This DWCIE Study is a prospective cohort study of patients fit to the FDA approved and marketed lotrafilcon A (Ciba Vision, Air Optix Night \& Day Aqua) soft contact lenses for daily wear (DW) with monthly disposal. 218 healthy myopic (nearsighted) or hyperopic (farsighted) patients with minimal or no astigmatism and no contraindications to DW lens use will be followed for 1 year. The primary outcome is the risk of development of a corneal inflammatory event (CIE) as defined by slit lamp findings and patient symptoms. The main exposure of interest is microbial contamination of study lenses.
Primary Outcome
Raw number of participants in each solution arm developing CIE over 12 month follow-up period
Interventions
- DEVICE Clear Care
- DEVICE lotrafilcon A contact lenses
- DEVICE Renu Multiplus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 218 participants |
| Start Date | 2009-11 |
| Est. Completion | 2012-02 |
| Phase | Phase 4 |
What the finished NCT00937105 record still lists
NCT00937105 is an interventional study that assigns participants to a tested intervention. The registered 218 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (58% lower).
The record links to 0 conditions, and to 3 interventions - of which Clear Care is the first listed.
NCT00937105 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00937105 about?
NCT00937105 is a clinical study titled "Daily Wear Corneal Infiltrative Event Study". This DWCIE Study is a prospective cohort study of patients fit to the FDA approved and marketed lotrafilcon A (Ciba Vision, Air Optix Night \& Day Aqua) soft contact lenses for daily wear (DW) with monthly disposal. 218 healthy myopic (nearsighted) or hyperopic (farsighted) patients with minimal or ...
What is the current status of trial NCT00937105?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 218 participants. The study started on 2009-11. Estimated completion is 2012-02.
What interventions are being tested in trial NCT00937105?
The interventions under investigation include: Clear Care (DEVICE), lotrafilcon A contact lenses (DEVICE), Renu Multiplus (DEVICE).
Who is sponsoring clinical trial NCT00937105?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00937105's enrollment target sits among peer trials
218 390th of 2000 higher than 1,608 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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