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COMPLETED Phase 1

Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments

NCT00920205 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to see how safe the study drug is and to determine the best dose to use in cancer patients in the future. The study drug is designed to reduce the activity of a protein known as "heat shock protein 90", or "Hsp90". Hsp90 is found in every cell in the human body and normally helps those cells (and the body) cope with stressful situations. In certain cancers, however, Hsp90 helps the cancer cells survive and grow. By reducing the activity of Hsp90, the study drug may slow the growth, and reduce the survival, of those cancer cells.

Conditions Studied

Interventions

  • DRUG MPC-3100 (an Hsp90 inhibitor)

Study Locations (3)

Nevada

  • Nevada Cancer Institute — Las Vegas

Pennsylvania

  • Fox Chase Cancer Center — Philadelphia

Texas

  • South Texas Accelerated Research Therapeutics — San Antonio

Trial Details

FieldValue
Enrollment Target 26 participants
Start Date 2009-06
Est. Completion 2011-06
Phase Phase 1

Sponsor

Myrexis

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00920205

The ClinicalTrials.gov registry entry for NCT00920205 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Myrexis, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 1 intervention — of which MPC-3100 (an Hsp90 inhibitor) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00920205 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Nevada, Pennsylvania, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00920205 about?

NCT00920205 is a clinical study titled "Safety Study of MPC-3100 in Cancer Patients Who Have Failed Other Treatments". The purpose of this study is to see how safe the study drug is and to determine the best dose to use in cancer patients in the future. The study drug is designed to reduce the activity of a protein known as "heat shock protein 90", or "Hsp90". Hsp90 is found in every cell in the human body and norm...

What is the current status of trial NCT00920205?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 26 participants. The study started on 2009-06. Estimated completion is 2011-06.

What conditions does trial NCT00920205 study?

This clinical trial studies the following conditions: Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00920205?

The interventions under investigation include: MPC-3100 (an Hsp90 inhibitor) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00920205?

This trial is sponsored by Myrexis, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00920205 being conducted?

This trial has 3 study locations across Nevada, Pennsylvania, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial