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NCT00918931 · ClinicalTrials.gov registry record · Phase 2

Obatoclax for Systemic Mastocytosis

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
3
Enrollment target

NCT00918931: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT00918931 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 3 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00918931, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
3 participants
Enrollment target

Study Summary

The goal of this clinical research study is to learn if obatoclax mesylate can help to control systemic mastocytosis. The safety of this drug will also be tested.

Primary Outcome

Response rate is defined as number of participants with objective response divided by number of participants evaluated. Objective response is complete response and partial response where 'complete response' constitutes total elimination of a symptom or sign of the disease; 'partial response' constitutes at least 50% improvement in a symptom or sign of the disease. Objective response definitions of response evaluated following guidelines proposed by Valent et al. (International working group cons

Interventions

  • DRUG Obatoclax Mesylate

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2009-06
Est. Completion 2010-10
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

Why NCT00918931 stopped before completion

NCT00918931 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Obatoclax Mesylate is the first listed.

NCT00918931 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00918931 about?

NCT00918931 is a clinical study titled "Obatoclax for Systemic Mastocytosis". The goal of this clinical research study is to learn if obatoclax mesylate can help to control systemic mastocytosis. The safety of this drug will also be tested.

What is the current status of trial NCT00918931?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 3 participants. The study started on 2009-06. Estimated completion is 2010-10.

What interventions are being tested in trial NCT00918931?

The interventions under investigation include: Obatoclax Mesylate (DRUG).

Who is sponsoring clinical trial NCT00918931?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00918931's enrollment target sits among peer trials

3 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00918931, the US trial registry maintained by the National Library of Medicine. NCT00918931 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.