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NCT00913614 · ClinicalTrials.gov registry record · Phase 1

Single Dose Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Evaluation of Eplivanserin in Children With Insomnia

A Phase 1 study, sponsored by Sanofi.

Completed
Registry status
Phase 1
Development phase
41
Enrollment target

NCT00913614 is a Phase 1 study that has completed, run by Sanofi. The registered enrollment target is 41 participants.

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The verdict

NCT00913614, a Phase 1 study, has completed, sponsored by Sanofi.

COMPLETED
Registry status
Phase 1
Development phase
41 participants
Enrollment target

Study Summary

Given the potential age-related differences in safety, tolerability, pharmacokinetics, and differences in sleep architecture in young children versus adolescent versus adult, studies to identify the appropriate drug and dosage for children of all ages are essential in addressing this health problem that impacts the child and their family. The objective of this study is to evaluate the safety, pharmacokinetics and preliminary efficacy of eplivanserin. Primary objective: to assess the safety and tolerability after administration of single ascending oral doses of eplivanserin to children aged 6-17 years with insomnia of various origins. To assess the pharmacokinetics of eplivanserin (and active metabolite: SR141342) after administration of single ascending oral doses of eplivanserin to children aged 6-17 years with insomnia of various origins. Secondary objective: to assess the effect of single ascending oral doses of eplivanserin on global sleep parameters and sleep architecture measured via polysomnography recordings in children aged 6-17 years old with insomnia of various origins.

Interventions

  • DRUG Eplivanserin (SR46349)

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2009-06
Est. Completion 2009-12
Phase Phase 1

Sponsor

Sanofi

713 total trials

What the Registry Record Tells You About NCT00913614

The ClinicalTrials.gov registry entry for NCT00913614 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Sanofi, which has 713 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Eplivanserin (SR46349) is the first listed.

NCT00913614 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00913614 about?

NCT00913614 is a clinical study titled "Single Dose Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Evaluation of Eplivanserin in Children With Insomnia". Given the potential age-related differences in safety, tolerability, pharmacokinetics, and differences in sleep architecture in young children versus adolescent versus adult, studies to identify the appropriate drug and dosage for children of all ages are essential in addressing this health problem ...

What is the current status of trial NCT00913614?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 41 participants. The study started on 2009-06. Estimated completion is 2009-12.

What interventions are being tested in trial NCT00913614?

The interventions under investigation include: Eplivanserin (SR46349) (DRUG).

Who is sponsoring clinical trial NCT00913614?

This trial is sponsored by Sanofi, which has 713 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.