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NCT00911963 · ClinicalTrials.gov registry record · Phase 1
Pharmacokinetics of Multiple Ascending Doses of VCH-222 in Subjects With Chronic Hepatitis C Infection
A Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 49
- Enrollment target
NCT00911963: Completed Phase 1 study, sponsored by Vertex Pharmaceuticals Incorporated.
NCT00911963 is a Phase 1 study that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 49 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00911963, a Phase 1 study, has completed, sponsored by Vertex Pharmaceuticals Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 49 participants
- Enrollment target
Study Summary
The purpose of this study is to assess antiviral activity when administered alone for 3 days or in combination with peginterferon and ribavirin for 12 weeks. This study will also evaluate the safety and tolerability of treatment with VCH-222 when given alone or in combination with peginterferon and ribavirin. The study will also evaluate the pharmacokinetic profile of VCH-222 in HCV infected subjects.
Interventions
- DRUG ribavirin
- BIOLOGICAL peginterferon alfa-2a
- DRUG VCH-222 or matching placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 49 participants |
| Start Date | 2009-04 |
| Est. Completion | 2012-09 |
| Phase | Phase 1 |
What the finished NCT00911963 record still lists
NCT00911963 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 49 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (18% lower).
The record links to 0 conditions, and to 3 interventions - of which ribavirin is the first listed.
NCT00911963 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00911963 about?
NCT00911963 is a clinical study titled "Pharmacokinetics of Multiple Ascending Doses of VCH-222 in Subjects With Chronic Hepatitis C Infection". The purpose of this study is to assess antiviral activity when administered alone for 3 days or in combination with peginterferon and ribavirin for 12 weeks. This study will also evaluate the safety and tolerability of treatment with VCH-222 when given alone or in combination with peginterferon and ...
What is the current status of trial NCT00911963?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 49 participants. The study started on 2009-04. Estimated completion is 2012-09.
What interventions are being tested in trial NCT00911963?
The interventions under investigation include: ribavirin (DRUG), peginterferon alfa-2a (BIOLOGICAL), VCH-222 or matching placebo (DRUG).
Who is sponsoring clinical trial NCT00911963?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00911963's enrollment target sits among peer trials
49 1017th of 2000 higher than 976 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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