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NCT00907972 · ClinicalTrials.gov registry record · Phase 2

The Effects of Vitamin D and Bone Loss in Parkinson's Disease

A Phase 2 study, sponsored by Memorial Medical Center.

Completed
Registry status
Phase 2
Development phase
23
Enrollment target

NCT00907972: Completed Phase 2 study, sponsored by Memorial Medical Center.

NCT00907972 is a Phase 2 study that has completed, run by Memorial Medical Center. The registered enrollment target is 23 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00907972, a Phase 2 study, has completed, sponsored by Memorial Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

Health care burdens from neurodegenerative diseases are expected to increase disproportionately. Increasing age also predisposes this same population to other chronic diseases including osteoporosis, a progressive systemic skeletal disease characterized by low bone mass, which leads to an increase susceptibility to fractures. In the United States, 44 million people are estimated to be at risk for osteoporosis and low bone mass emphasizing the enormity of this public health problem. Parkinson's disease is a progressive neurodegenerative disorder affecting about 1 million people. Evidence indicates that Parkinson's disease patients are at a higher risk for low bone mineral density, which can contribute to increased fractures compared to healthy subjects. In fact, several risk factors of osteoporosis in patients with PD have been identified, including advanced stages of PD, low body mass index, inadequate sunlight exposure and decreased vitamin D levels. Some or all of these factors in conjunction with decreased immobilization that may occur with PD, put patients at increased risks for fractures. Few studies however have examined bone markers in PD patients. Even fewer studies have examined the impact of Vitamin D supplementation on bone metabolism and mineralization in PD patients. Vitamin D is an essential component in bone health, promoting calcium absorption in the gut and maintaining adequate serum calcium and phosphate concentrations, which enable normal mineralization of bone.

Interventions

  • OTHER Placebo
  • DIETARY_SUPPLEMENT Vitamin D3

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2009-09
Est. Completion 2013-01
Phase Phase 2
Memorial Medical Center

7 total trials

What the finished NCT00907972 record still lists

NCT00907972 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00907972 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00907972 about?

NCT00907972 is a clinical study titled "The Effects of Vitamin D and Bone Loss in Parkinson's Disease". Health care burdens from neurodegenerative diseases are expected to increase disproportionately. Increasing age also predisposes this same population to other chronic diseases including osteoporosis, a progressive systemic skeletal disease characterized by low bone mass, which leads to an increase s...

What is the current status of trial NCT00907972?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2009-09. Estimated completion is 2013-01.

What interventions are being tested in trial NCT00907972?

The interventions under investigation include: Placebo (OTHER), Vitamin D3 (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT00907972?

This trial is sponsored by Memorial Medical Center, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00907972's enrollment target sits among peer trials

23 1784th of 2000 higher than 211 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00907972, the US trial registry maintained by the National Library of Medicine. NCT00907972 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.