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NCT00903760 · ClinicalTrials.gov registry record · Phase 2
Decitabine and Clofarabine in Higher Risk Myelodysplastic Syndromes (MDS)
A Phase 2 study, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 42
- Enrollment target
NCT00903760: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.
NCT00903760 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 42 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00903760, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 42 participants
- Enrollment target
Study Summary
The goal of this clinical research study is to learn if sequential administration of decitabine and clofarabine can help to control MDS better than decitabine alone. The safety of this drug combination will also be studied.
Primary Outcome
Percentage of participants with event free survival at 1 year. Event free survival (EFS) where event is defined as either death or transformation to acute myeloid leukemia (AML) (marrow and/or blood blasts \>/= 20%)
Interventions
- DRUG Decitabine
- DRUG Clofarabine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2010-01 |
| Est. Completion | 2015-06 |
| Phase | Phase 2 |
What the finished NCT00903760 record still lists
NCT00903760 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 42 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which Decitabine is the first listed.
NCT00903760 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00903760 about?
NCT00903760 is a clinical study titled "Decitabine and Clofarabine in Higher Risk Myelodysplastic Syndromes (MDS)". The goal of this clinical research study is to learn if sequential administration of decitabine and clofarabine can help to control MDS better than decitabine alone. The safety of this drug combination will also be studied.
What is the current status of trial NCT00903760?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2010-01. Estimated completion is 2015-06.
What interventions are being tested in trial NCT00903760?
The interventions under investigation include: Decitabine (DRUG), Clofarabine (DRUG).
Who is sponsoring clinical trial NCT00903760?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00903760's enrollment target sits among peer trials
42 1339th of 2000 higher than 649 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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