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NCT00901394 · ClinicalTrials.gov registry record · NA
Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 63
- Enrollment target
NCT00901394: Completed NA study, sponsored by Washington University School of Medicine.
NCT00901394 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 63 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00901394, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 63 participants
- Enrollment target
Study Summary
The goal of this study is to find out if giving intravenous B-vitamins before general anesthesia with nitrous oxide prevents the increase in homocysteine, a metabolite that has been linked to cardiovascular complications.
Primary Outcome
Difference between baseline (pre-operative) and peak postoperative (i.e., maximum of postoperative value obtained within 30 minutes after anesthesia end time and morning of post-operative day 1) tHcy concentration . Of note: there were no secondary outcomes.
Interventions
- OTHER Placebo
- DRUG B12-Folic Acid, nitrous oxide
- DRUG Nitrous oxide (NO) and placebo
- OTHER oxygen nitrogen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 63 participants |
| Start Date | 2009-03 |
| Est. Completion | 2010-01 |
| Phase | NA |
What the finished NCT00901394 record still lists
NCT00901394 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 63 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT00901394 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00901394 about?
NCT00901394 is a clinical study titled "Vitamin B12 and Folate Administration on Homocysteine Concentrations After Nitrous Oxide Anesthesia". The goal of this study is to find out if giving intravenous B-vitamins before general anesthesia with nitrous oxide prevents the increase in homocysteine, a metabolite that has been linked to cardiovascular complications.
What is the current status of trial NCT00901394?
This trial is currently completed. It is a NA study. The enrollment target is 63 participants. The study started on 2009-03. Estimated completion is 2010-01.
What interventions are being tested in trial NCT00901394?
The interventions under investigation include: Placebo (OTHER), B12-Folic Acid, nitrous oxide (DRUG), Nitrous oxide (NO) and placebo (DRUG), oxygen nitrogen (OTHER).
Who is sponsoring clinical trial NCT00901394?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00901394's enrollment target sits among peer trials
63 1157th of 2000 higher than 844 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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