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NCT00901238 · ClinicalTrials.gov registry record · Phase 1

Intra-arterial Chemotherapy(Chemosurgery) for Retinoblastoma

A Phase 1 study, sponsored by Weill Medical College of Cornell University.

Completed
Registry status
Phase 1
Development phase
100
Enrollment target

NCT00901238: Completed Phase 1 study, sponsored by Weill Medical College of Cornell University.

NCT00901238 is a Phase 1 study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 100 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00901238, a Phase 1 study, has completed, sponsored by Weill Medical College of Cornell University.

COMPLETED
Registry status
Phase 1
Development phase
100 participants
Enrollment target

Study Summary

Conventional treatments of retinoblastoma involves laser photocoagulation, cryotherapy (freezing of the tumor), plaque radiotherapy,external beam radiotherapy, and intravenous chemotherapy. Enucleation (removing of the eye)is the last option when the tumor cannot be controlled otherwise. However,many children with retinoblastoma present with advanced intraocular disease for which enucleation is the only option. Intra-arterial chemotherapy (Chemosurgery)delivers anti-tumor drug directly into the ophthalmic artery (the artery feeding the eye) in order to increase the dose of drug reaching the tumor while minimizing toxicity to the rest of the body.

Interventions

  • PROCEDURE Intra-arterial Chemotherapy

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2006-05
Est. Completion 2009-07
Phase Phase 1

What the finished NCT00901238 record still lists

NCT00901238 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher).

The record links to 0 conditions, and to 1 intervention - of which Intra-arterial Chemotherapy is the first listed.

NCT00901238 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00901238 about?

NCT00901238 is a clinical study titled "Intra-arterial Chemotherapy(Chemosurgery) for Retinoblastoma". Conventional treatments of retinoblastoma involves laser photocoagulation, cryotherapy (freezing of the tumor), plaque radiotherapy,external beam radiotherapy, and intravenous chemotherapy. Enucleation (removing of the eye)is the last option when the tumor cannot be controlled otherwise. However,man...

What is the current status of trial NCT00901238?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2006-05. Estimated completion is 2009-07.

What interventions are being tested in trial NCT00901238?

The interventions under investigation include: Intra-arterial Chemotherapy (PROCEDURE).

Who is sponsoring clinical trial NCT00901238?

This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00901238's enrollment target sits among peer trials

100 546th of 2000 higher than 1,411 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00901238, the US trial registry maintained by the National Library of Medicine. NCT00901238 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.