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NCT00892801 · ClinicalTrials.gov registry record · Phase 1

Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer

A Phase 1 study, sponsored by Vanderbilt-Ingram Cancer Center.

Terminated
Registry status
Phase 1
Development phase
5
Enrollment target

NCT00892801 is a Phase 1 study that was terminated before completion, run by Vanderbilt-Ingram Cancer Center. The registered enrollment target is 5 participants.

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The verdict

NCT00892801, a Phase 1 study, was terminated before completion, sponsored by Vanderbilt-Ingram Cancer Center.

TERMINATED
Registry status
Phase 1
Development phase
5 participants
Enrollment target

Study Summary

RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving everolimus together with whole-brain radiation therapy may kill more tumor cells. PURPOSE: This phase I/II trial is studying the side effects and best dose of everolimus and to see how well it works when given together with whole-brain radiation therapy in treating patients with brain metastasis from non-small cell lung cancer.

Interventions

  • DRUG RAD001
  • RADIATION whole-brain radiation therapy

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2009-05
Est. Completion 2011-02
Phase Phase 1

Sponsor

Vanderbilt-Ingram Cancer Center

189 total trials

What the Registry Record Tells You About NCT00892801

The ClinicalTrials.gov registry entry for NCT00892801 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Vanderbilt-Ingram Cancer Center, which has 189 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which RAD001 is the first listed.

NCT00892801 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00892801 about?

NCT00892801 is a clinical study titled "Everolimus and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastasis From Non-Small Cell Lung Cancer". RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving everolimus together with whole-brain radiation therapy may kill more tumor ce...

What is the current status of trial NCT00892801?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 5 participants. The study started on 2009-05. Estimated completion is 2011-02.

What interventions are being tested in trial NCT00892801?

The interventions under investigation include: RAD001 (DRUG), whole-brain radiation therapy (RADIATION).

Who is sponsoring clinical trial NCT00892801?

This trial is sponsored by Vanderbilt-Ingram Cancer Center, which has 189 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.