Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00890890 · ClinicalTrials.gov registry record · Phase 2

A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Terminated
Registry status
Phase 2
Development phase
263
Enrollment target

NCT00890890: Clinical Trial Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT00890890 is a Phase 2 study that was terminated before completion, run by Bristol-Myers Squibb. The registered enrollment target is 263 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00890890, a Phase 2 study, was terminated before completion, sponsored by Bristol-Myers Squibb.

TERMINATED
Registry status
Phase 2
Development phase
263 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and tolerability of BMS-708163 in patients with Prodromal Alzheimer's disease over a treatment period of a minimum of 104-weeks. In addition patients will be seen for safety visits at 4 and 12 weeks post treatment.

Interventions

  • DRUG Placebo
  • DRUG Avagacestat

Trial Details

FieldValue
Enrollment Target 263 participants
Start Date 2009-05
Est. Completion 2013-07
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

Why NCT00890890 stopped before completion

NCT00890890 is an interventional study that assigns participants to a tested intervention. The registered 263 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (98% higher).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT00890890 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00890890 about?

NCT00890890 is a clinical study titled "A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease". The purpose of this study is to determine the safety and tolerability of BMS-708163 in patients with Prodromal Alzheimer's disease over a treatment period of a minimum of 104-weeks. In addition patients will be seen for safety visits at 4 and 12 weeks post treatment.

What is the current status of trial NCT00890890?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 263 participants. The study started on 2009-05. Estimated completion is 2013-07.

What interventions are being tested in trial NCT00890890?

The interventions under investigation include: Placebo (DRUG), Avagacestat (DRUG).

Who is sponsoring clinical trial NCT00890890?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00890890's enrollment target sits among peer trials

263 210th of 2000 higher than 1,791 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT04067336 · 263 participants · Phase 1

    First in Human Study of Ziftomenib in Relapsed or Refractory Acute Myeloid Leukemia

  • NCT06234423 · 263 participants · Phase 1

    A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

  • NCT06724627 · 263 participants · NA

    Application of the Belle.AI Dermatological Image Reference System for Patient Diagnosis in an Active Clinical Setting

  • NCT04101669 · 264 participants · NA

    RESET System Pivotal Trial (Rev F)

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00890890, the US trial registry maintained by the National Library of Medicine. NCT00890890 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.