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NCT00882206 · ClinicalTrials.gov registry record · Phase 2

Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia

A Phase 2 study, sponsored by Masonic Cancer Center, University of Minnesota.

Terminated
Registry status
Phase 2
Development phase
15
Enrollment target

NCT00882206 is a Phase 2 study that was terminated before completion, run by Masonic Cancer Center, University of Minnesota. The registered enrollment target is 15 participants.

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The verdict

NCT00882206, a Phase 2 study, was terminated before completion, sponsored by Masonic Cancer Center, University of Minnesota.

TERMINATED
Registry status
Phase 2
Development phase
15 participants
Enrollment target

Study Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Decitabine and vorinostat may alter the cancer cells by reversing the cancer pathways needed for cell growth. Giving more than one drug (combination chemotherapy) together with decitabine and vorinostat may kill more cancer cells than with chemotherapy alone. PURPOSE: This phase II trial is studying how well giving decitabine and vorinostat together with combination chemotherapy works in treating patients with acute lymphoblastic leukemia or lymphoblastic lymphoma that has relapsed or not responded to treatment.

Interventions

  • DRUG imatinib mesylate
  • DRUG decitabine
  • DRUG methotrexate
  • DRUG doxorubicin hydrochloride
  • DRUG cytarabine

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2009-04
Est. Completion 2013-01
Phase Phase 2

What the Registry Record Tells You About NCT00882206

The ClinicalTrials.gov registry entry for NCT00882206 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 15 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Masonic Cancer Center, University of Minnesota, which has 249 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which imatinib mesylate is the first listed.

NCT00882206 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00882206 about?

NCT00882206 is a clinical study titled "Pre-reinductive Decitabine and Vorinostat in Relapsed Lymphoblastic Lymphoma or Acute Lymphoblastic Leukemia". RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Decitabine and vorinostat may alter the cancer cells by reversing the cancer pathways needed for cell growth. Giving more than one drug (com...

What is the current status of trial NCT00882206?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 15 participants. The study started on 2009-04. Estimated completion is 2013-01.

What interventions are being tested in trial NCT00882206?

The interventions under investigation include: imatinib mesylate (DRUG), decitabine (DRUG), methotrexate (DRUG), doxorubicin hydrochloride (DRUG), cytarabine (DRUG).

Who is sponsoring clinical trial NCT00882206?

This trial is sponsored by Masonic Cancer Center, University of Minnesota, which has 249 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.