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NCT00879970 · ClinicalTrials.gov registry record · Phase 4
Thiazolidinedione Intervention With Vitamin D Evaluation
A Phase 4 study, sponsored by GlaxoSmithKline.
- Terminated
- Registry status
- Phase 4
- Development phase
- 1,332
- Enrollment target
NCT00879970: Clinical Trial Phase 4 study, sponsored by GlaxoSmithKline.
NCT00879970 is a Phase 4 study that was terminated before completion, run by GlaxoSmithKline. The registered enrollment target is 1,332 participants, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (157% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00879970, a Phase 4 study, was terminated before completion, sponsored by GlaxoSmithKline.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 1,332 participants
- Enrollment target
Study Summary
This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard of care without rosiglitazone or pioglitazone in patients with type 2 diabetes who have a history of or are at risk for cardiovascular disease. The second question will compare the effects of long-term supplementation of vitamin D on death and cancer
Primary Outcome
An event adjudication committee (EAC) adjudicated all occurrences of the components of the composite cardiovascular (CV; related to heart) outcome for TZD. Components are the first occurrence of cardiovascular death for which a non-heart-related cause has not been identified; non-fatal myocardial infarction (MI) (death of heart muscle from sudden blockage of a coronary artery by blood clot not leading to death); and non-fatal stroke (rapidly developing loss of brain function\[s\] due to disturba
Interventions
- DIETARY_SUPPLEMENT Placebo
- DRUG placebo
- DIETARY_SUPPLEMENT Vitamin D
- DRUG pioglitazone
- DRUG rosiglitazone
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,332 participants |
| Start Date | 2009-05 |
| Est. Completion | 2010-11 |
| Phase | Phase 4 |
Why NCT00879970 stopped before completion
NCT00879970 is an interventional study that assigns participants to a tested intervention. Its 1,332 participants enrollment target places it among the larger protocols in the corpus, above the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (157% higher).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT00879970 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00879970 about?
NCT00879970 is a clinical study titled "Thiazolidinedione Intervention With Vitamin D Evaluation". This study will answer two separate questions. The first question is to test the cardiovascular effects of long-term treatment with rosiglitazone or pioglitazone when used as part of standard of care compared to similar standard of care without rosiglitazone or pioglitazone in patients with type 2 ...
What is the current status of trial NCT00879970?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 1,332 participants. The study started on 2009-05. Estimated completion is 2010-11.
What interventions are being tested in trial NCT00879970?
The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), placebo (DRUG), Vitamin D (DIETARY_SUPPLEMENT), pioglitazone (DRUG), rosiglitazone (DRUG).
Who is sponsoring clinical trial NCT00879970?
This trial is sponsored by GlaxoSmithKline, which has 1,345 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00879970's enrollment target sits among peer trials
1,332 58th of 2000 higher than 1,943 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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