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NCT00869440 · ClinicalTrials.gov registry record · Phase 2
Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy
A Phase 2 study, sponsored by Paion UK.
- Completed
- Registry status
- Phase 2
- Development phase
- 100
- Enrollment target
NCT00869440: Completed Phase 2 study, sponsored by Paion UK.
NCT00869440 is a Phase 2 study that has completed, run by Paion UK. The registered enrollment target is 100 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00869440, a Phase 2 study, has completed, sponsored by Paion UK.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 100 participants
- Enrollment target
Study Summary
The purpose of this study was to assess the safety and efficacy of CNS 7056 as a procedural sedative at three dose levels compared to midazolam during a diagnostic upper GI endoscopy.
Primary Outcome
Success of the procedure is a composite endpoint consisting of: MOAA/S scores ≤4 on three consecutive measurements after administration of study drug AND completion of the endoscopy procedure AND no requirement for rescue sedative medication AND no requirement for manual or mechanical ventilation
Interventions
- DRUG Midazolam
- DRUG CNS 7056
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2009-03 |
| Est. Completion | 2009-09 |
| Phase | Phase 2 |
What the finished NCT00869440 record still lists
NCT00869440 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (25% lower).
The record links to 0 conditions, and to 2 interventions - of which Midazolam is the first listed.
NCT00869440 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00869440 about?
NCT00869440 is a clinical study titled "Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI Endoscopy". The purpose of this study was to assess the safety and efficacy of CNS 7056 as a procedural sedative at three dose levels compared to midazolam during a diagnostic upper GI endoscopy.
What is the current status of trial NCT00869440?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2009-03. Estimated completion is 2009-09.
What interventions are being tested in trial NCT00869440?
The interventions under investigation include: Midazolam (DRUG), CNS 7056 (DRUG).
Who is sponsoring clinical trial NCT00869440?
This trial is sponsored by Paion UK, which has 9 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00869440's enrollment target sits among peer trials
100 672nd of 2000 higher than 1,263 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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