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NCT00868842 · ClinicalTrials.gov registry record

Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis

A clinical trial, sponsored by Virginia Commonwealth University.

Completed
Registry status
10
Enrollment target

NCT00868842 is a clinical trial that has completed, run by Virginia Commonwealth University. The registered enrollment target is 10 participants.

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The verdict

NCT00868842 has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
10 participants
Enrollment target

Study Summary

This is an open-label, single-center study of whether oral penicillin desensitization of healthy sensitive subjects results in allergen cross-desensitization of mast cells by skin testing and desensitization of peripheral blood basophils. The primary endpoint(s) will be PC3 prick skin test values to penicillin, aeroallergen(s) and codeine. Secondary endpoints will be levels of Syk in purified basophils determined by flow cytometry (mean fluorescence intensity) and basophil degranulation (% tryptase release) to anti-FcåRI and to calcium ionophore.

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2009-01
Est. Completion 2012-06

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT00868842

The ClinicalTrials.gov registry entry for NCT00868842 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00868842 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00868842 about?

NCT00868842 is a clinical study titled "Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis". This is an open-label, single-center study of whether oral penicillin desensitization of healthy sensitive subjects results in allergen cross-desensitization of mast cells by skin testing and desensitization of peripheral blood basophils. The primary endpoint(s) will be PC3 prick skin test values to...

What is the current status of trial NCT00868842?

This trial is currently completed. The enrollment target is 10 participants. The study started on 2009-01. Estimated completion is 2012-06.

Who is sponsoring clinical trial NCT00868842?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.