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NCT00868842 · ClinicalTrials.gov registry record
Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis
A clinical trial, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- 10
- Enrollment target
NCT00868842: Completed study, sponsored by Virginia Commonwealth University.
NCT00868842 is a clinical trial that has completed, run by Virginia Commonwealth University. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00868842 has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- 10 participants
- Enrollment target
Study Summary
This is an open-label, single-center study of whether oral penicillin desensitization of healthy sensitive subjects results in allergen cross-desensitization of mast cells by skin testing and desensitization of peripheral blood basophils. The primary endpoint(s) will be PC3 prick skin test values to penicillin, aeroallergen(s) and codeine. Secondary endpoints will be levels of Syk in purified basophils determined by flow cytometry (mean fluorescence intensity) and basophil degranulation (% tryptase release) to anti-FcåRI and to calcium ionophore.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2009-01 |
| Est. Completion | 2012-06 |
What the finished NCT00868842 record still lists
NCT00868842 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT00868842 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00868842 about?
NCT00868842 is a clinical study titled "Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis". This is an open-label, single-center study of whether oral penicillin desensitization of healthy sensitive subjects results in allergen cross-desensitization of mast cells by skin testing and desensitization of peripheral blood basophils. The primary endpoint(s) will be PC3 prick skin test values to...
What is the current status of trial NCT00868842?
This trial is currently completed. The enrollment target is 10 participants. The study started on 2009-01. Estimated completion is 2012-06.
Who is sponsoring clinical trial NCT00868842?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
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