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NCT00859859 · ClinicalTrials.gov registry record · Phase 1
Vagus Nerve Stimulation in Rheumatoid Arthritis
A Phase 1 study, sponsored by Northwell Health.
- Terminated
- Registry status
- Phase 1
- Development phase
- 23
- Enrollment target
NCT00859859: Clinical Trial Phase 1 study, sponsored by Northwell Health.
NCT00859859 is a Phase 1 study that was terminated before completion, run by Northwell Health. The registered enrollment target is 23 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00859859, a Phase 1 study, was terminated before completion, sponsored by Northwell Health.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 23 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the short-term effects of vagus nerve stimulation (VNS) by auricular stimulation (stimulation of the auricular branch of the vagus nerve which innervates the ear) in rheumatoid arthritis (RA). RA is characterized by a chronic systemic inflammation affecting the joints but also carries an increased risk for extra-articular manifestations as well as other organ manifestations such as cardiovascular disease (CVD), which significantly contributes to morbidity and mortality in this disorder.
Interventions
- DEVICE Vagus Nerve Stimulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2006-10 |
| Est. Completion | 2009-02 |
| Phase | Phase 1 |
Why NCT00859859 stopped before completion
NCT00859859 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 1 intervention - of which Vagus Nerve Stimulation is the first listed.
NCT00859859 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00859859 about?
NCT00859859 is a clinical study titled "Vagus Nerve Stimulation in Rheumatoid Arthritis". The purpose of this study is to examine the short-term effects of vagus nerve stimulation (VNS) by auricular stimulation (stimulation of the auricular branch of the vagus nerve which innervates the ear) in rheumatoid arthritis (RA). RA is characterized by a chronic systemic inflammation affecting th...
What is the current status of trial NCT00859859?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 23 participants. The study started on 2006-10. Estimated completion is 2009-02.
What interventions are being tested in trial NCT00859859?
The interventions under investigation include: Vagus Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT00859859?
This trial is sponsored by Northwell Health, which has 370 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00859859's enrollment target sits among peer trials
23 1596th of 2000 higher than 400 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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