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NCT00859495 · ClinicalTrials.gov registry record · Phase 2
Trimodal Lung-Sparing Treatment of Pleural Mesothelioma
A Phase 2 study, sponsored by Columbia University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 9
- Enrollment target
NCT00859495: Clinical Trial Phase 2 study, sponsored by Columbia University.
NCT00859495 is a Phase 2 study that was terminated before completion, run by Columbia University. The registered enrollment target is 9 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00859495, a Phase 2 study, was terminated before completion, sponsored by Columbia University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 9 participants
- Enrollment target
Study Summary
The primary objective of the study is to determine the feasibility (as determined by lack of serious adverse events) and tolerability (as determined by patient's ability to complete the study) of a multimodal lung sparing regimen of surgery, interpleural and intravenous chemotherapy, and local P-32 irradiation for malignant pleural mesothelioma.
Primary Outcome
To determine the feasibility of multimodal lung sparing regimen. Intrapleural chemotherapy (12 weeks) will be administered within two weeks after surgery. Approximately 30 days post last dose of chemotherapy (+/- 14 days), the patient should be reassessed for resolution of any treatment-related toxicity which may have occurred during the course of study participation.
Interventions
- DRUG Cisplatin
- DRUG Doxorubicin
- DRUG Pemetrexed
- RADIATION Radiotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2008-02 |
| Est. Completion | 2012-02 |
| Phase | Phase 2 |
Why NCT00859495 stopped before completion
NCT00859495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 4 interventions - of which Cisplatin is the first listed.
NCT00859495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00859495 about?
NCT00859495 is a clinical study titled "Trimodal Lung-Sparing Treatment of Pleural Mesothelioma". The primary objective of the study is to determine the feasibility (as determined by lack of serious adverse events) and tolerability (as determined by patient's ability to complete the study) of a multimodal lung sparing regimen of surgery, interpleural and intravenous chemotherapy, and local P-32 ...
What is the current status of trial NCT00859495?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 9 participants. The study started on 2008-02. Estimated completion is 2012-02.
What interventions are being tested in trial NCT00859495?
The interventions under investigation include: Cisplatin (DRUG), Doxorubicin (DRUG), Pemetrexed (DRUG), Radiotherapy (RADIATION).
Who is sponsoring clinical trial NCT00859495?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00859495's enrollment target sits among peer trials
9 1989th of 2000 higher than 11 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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