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NCT00858871 · ClinicalTrials.gov registry record · Phase 3

First Line Hepato Cellular Carcinoma (HCC)

A Phase 3 study, sponsored by Bristol-Myers Squibb.

Completed
Registry status
Phase 3
Development phase
1,714
Enrollment target

NCT00858871: Completed Phase 3 study, sponsored by Bristol-Myers Squibb.

NCT00858871 is a Phase 3 study that has completed, run by Bristol-Myers Squibb. The registered enrollment target is 1,714 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (122% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00858871, a Phase 3 study, has completed, sponsored by Bristol-Myers Squibb.

COMPLETED
Registry status
Phase 3
Development phase
1,714 participants
Enrollment target

Study Summary

The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.

Interventions

  • DRUG Placebo
  • DRUG Sorafenib
  • DRUG Brivanib

Trial Details

FieldValue
Enrollment Target 1,714 participants
Start Date 2009-05
Est. Completion 2013-09
Phase Phase 3
Bristol-Myers Squibb

1,025 total trials

What the finished NCT00858871 record still lists

NCT00858871 is an interventional study that assigns participants to a tested intervention. Its 1,714 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (122% higher).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00858871 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00858871 about?

NCT00858871 is a clinical study titled "First Line Hepato Cellular Carcinoma (HCC)". The purpose of this study is to compare the overall survival of brivanib versus sorafenib in subjects with advanced HCC who have not received prior systemic therapy.

What is the current status of trial NCT00858871?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,714 participants. The study started on 2009-05. Estimated completion is 2013-09.

What interventions are being tested in trial NCT00858871?

The interventions under investigation include: Placebo (DRUG), Sorafenib (DRUG), Brivanib (DRUG).

Who is sponsoring clinical trial NCT00858871?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00858871's enrollment target sits among peer trials

1,714 130th of 2000 higher than 1,870 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00858871, the US trial registry maintained by the National Library of Medicine. NCT00858871 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.