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NCT00857519 · ClinicalTrials.gov registry record · NA
A Study of the Effectiveness of a Local Injection of Chemotherapy for Retinoblastoma
A NA study, sponsored by Wills Eye.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT00857519: Completed NA study, sponsored by Wills Eye.
NCT00857519 is a NA study that has completed, run by Wills Eye. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00857519, a NA study, has completed, sponsored by Wills Eye.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
Over the past 15 years, intravenous chemotherapy has become the most popular conservative (eye-saving) method for retinoblastoma treatment because it is often effective and usually safe. In recent years, there has been much interest in providing highly focused (focal) chemotherapy to a diseased organ including the liver, brain, and eye. With focused chemotherapy, the chemotherapy drugs are injected directly into the ophthalmic artery (the artery that supplies blood to the eye). A benefit of focal chemotherapy delivery is that it decreases the chance of toxicity to other organs such as bone marrow suppression (causing low blood counts) and the development of other cancers in the future.
Interventions
- DRUG Melphalan, Carboplatin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2009-01 |
| Est. Completion | 2014-04 |
| Phase | NA |
What the finished NCT00857519 record still lists
NCT00857519 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Melphalan, Carboplatin is the first listed.
NCT00857519 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00857519 about?
NCT00857519 is a clinical study titled "A Study of the Effectiveness of a Local Injection of Chemotherapy for Retinoblastoma". Over the past 15 years, intravenous chemotherapy has become the most popular conservative (eye-saving) method for retinoblastoma treatment because it is often effective and usually safe. In recent years, there has been much interest in providing highly focused (focal) chemotherapy to a diseased orga...
What is the current status of trial NCT00857519?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2009-01. Estimated completion is 2014-04.
What interventions are being tested in trial NCT00857519?
The interventions under investigation include: Melphalan, Carboplatin (DRUG).
Who is sponsoring clinical trial NCT00857519?
This trial is sponsored by Wills Eye, which has 59 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00857519's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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