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NCT00850577 · ClinicalTrials.gov registry record · Phase 2

Ph II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung Cancer

A Phase 2 study, sponsored by Bristol-Myers Squibb.

Terminated
Registry status
Phase 2
Development phase
255
Enrollment target

NCT00850577: Clinical Trial Phase 2 study, sponsored by Bristol-Myers Squibb.

NCT00850577 is a Phase 2 study that was terminated before completion, run by Bristol-Myers Squibb. The registered enrollment target is 255 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00850577, a Phase 2 study, was terminated before completion, sponsored by Bristol-Myers Squibb.

TERMINATED
Registry status
Phase 2
Development phase
255 participants
Enrollment target

Study Summary

The purpose of this study is to determine the efficacy of CT-322 comparative to bevacizumab, both in combination with carboplatin and paclitaxel in the treatment of chemonaive subjects with recurrent or advanced non-squamous NSCLC

Interventions

  • DRUG Bevacizumab
  • DRUG Carboplatin
  • DRUG Paclitaxel
  • DRUG CT-322
  • DRUG Bevacizumab placebo (ie saline solution)

Trial Details

FieldValue
Enrollment Target 255 participants
Start Date 2009-06
Est. Completion 2013-08
Phase Phase 2
Bristol-Myers Squibb

1,025 total trials

Why NCT00850577 stopped before completion

NCT00850577 is an interventional study that assigns participants to a tested intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (92% higher).

The record links to 0 conditions, and to 5 interventions - of which Bevacizumab is the first listed.

NCT00850577 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00850577 about?

NCT00850577 is a clinical study titled "Ph II of a Novel Anti-angiogenic Agent in Combination With Chemotherapy for the Treatment of Non-Small Cell Lung Cancer". The purpose of this study is to determine the efficacy of CT-322 comparative to bevacizumab, both in combination with carboplatin and paclitaxel in the treatment of chemonaive subjects with recurrent or advanced non-squamous NSCLC

What is the current status of trial NCT00850577?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 255 participants. The study started on 2009-06. Estimated completion is 2013-08.

What interventions are being tested in trial NCT00850577?

The interventions under investigation include: Bevacizumab (DRUG), Carboplatin (DRUG), Paclitaxel (DRUG), CT-322 (DRUG), Bevacizumab placebo (ie saline solution) (DRUG).

Who is sponsoring clinical trial NCT00850577?

This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00850577's enrollment target sits among peer trials

255 218th of 2000 higher than 1,782 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00850577, the US trial registry maintained by the National Library of Medicine. NCT00850577 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.