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NCT00846287 · ClinicalTrials.gov registry record · NA

Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI

A NA study, sponsored by University of Massachusetts, Worcester.

Completed
Registry status
NA
Development phase
16
Enrollment target

NCT00846287: Completed NA study, sponsored by University of Massachusetts, Worcester.

NCT00846287 is a NA study that has completed, run by University of Massachusetts, Worcester. The registered enrollment target is 16 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00846287, a NA study, has completed, sponsored by University of Massachusetts, Worcester.

COMPLETED
Registry status
NA
Development phase
16 participants
Enrollment target

Study Summary

The purpose of this study is to determine efficacy of MR imaging with hyperpolarized helium-3 gas in COPD patients both before and after treatment.

Primary Outcome

Subjects had hyperpolarized helium-3 MR scans completed before administration of an intervention and 2 hours after administration. These images were compared as described: The change in the total ventilation volume (Litres) measured in the hyperpolarized helium-3 MR image from pre-nebulizer inhalation to post-nebulizer inhalation.

Interventions

  • DRUG Placebo
  • DRUG Hyperpolarized Helium-3
  • DRUG Aformoterol

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2008-11
Est. Completion 2011-04
Phase NA

What the finished NCT00846287 record still lists

NCT00846287 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT00846287 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00846287 about?

NCT00846287 is a clinical study titled "Assessment of Arformoterol for Chronic Obstructive Pulmonary Disease (COPD) Using Hyperpolarized 3He MRI". The purpose of this study is to determine efficacy of MR imaging with hyperpolarized helium-3 gas in COPD patients both before and after treatment.

What is the current status of trial NCT00846287?

This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2008-11. Estimated completion is 2011-04.

What interventions are being tested in trial NCT00846287?

The interventions under investigation include: Placebo (DRUG), Hyperpolarized Helium-3 (DRUG), Aformoterol (DRUG).

Who is sponsoring clinical trial NCT00846287?

This trial is sponsored by University of Massachusetts, Worcester, which has 240 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00846287's enrollment target sits among peer trials

16 1871st of 2000 higher than 120 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00846287, the US trial registry maintained by the National Library of Medicine. NCT00846287 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.