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NCT00845299 · ClinicalTrials.gov registry record · Phase 2

Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma

A Phase 2 study, sponsored by Mati Therapeutics.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target

NCT00845299: Completed Phase 2 study, sponsored by Mati Therapeutics.

NCT00845299 is a Phase 2 study that has completed, run by Mati Therapeutics. The registered enrollment target is 40 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00845299, a Phase 2 study, has completed, sponsored by Mati Therapeutics.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this study is to determine the effect of artificial tears preserved with Benzalkonium Chloride (AT-BAK) on the IOP response to the L-PPDS and to evaluate the safety of the L-PPDS in subjects with OH or OAG following treatment.

Interventions

  • DRUG Latanoprost punctal plug
  • DRUG artificial tears preserved with Benzalkonium Chloride

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2009-01
Est. Completion 2009-12
Phase Phase 2
Mati Therapeutics

12 total trials

What the finished NCT00845299 record still lists

NCT00845299 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (70% lower).

The record links to 0 conditions, and to 2 interventions - of which Latanoprost punctal plug is the first listed.

NCT00845299 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00845299 about?

NCT00845299 is a clinical study titled "Study of the Effects of Artificial Tears on the Response to the Latanoprost Punctal Plug Delivery System in Subjects With Ocular Hypertension or Open-Angle Glaucoma". The purpose of this study is to determine the effect of artificial tears preserved with Benzalkonium Chloride (AT-BAK) on the IOP response to the L-PPDS and to evaluate the safety of the L-PPDS in subjects with OH or OAG following treatment.

What is the current status of trial NCT00845299?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2009-01. Estimated completion is 2009-12.

What interventions are being tested in trial NCT00845299?

The interventions under investigation include: Latanoprost punctal plug (DRUG), artificial tears preserved with Benzalkonium Chloride (DRUG).

Who is sponsoring clinical trial NCT00845299?

This trial is sponsored by Mati Therapeutics, which has 12 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00845299's enrollment target sits among peer trials

40 1362nd of 2000 higher than 542 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00845299, the US trial registry maintained by the National Library of Medicine. NCT00845299 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.