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NCT00844077 · ClinicalTrials.gov registry record
Preliminary Longitudinal Validation of Biomarkers Predictive of Barrett's Esophagus
A clinical trial, sponsored by University of Michigan.
- Completed
- Registry status
- 255
- Enrollment target
NCT00844077: Completed study, sponsored by University of Michigan.
NCT00844077 is a clinical trial that has completed, run by University of Michigan. The registered enrollment target is 255 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00844077 has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 255 participants
- Enrollment target
Study Summary
Barrett's esophagus can progress to esophageal cancer, but it doesn't always. Current treatment is frequent surveillance via upper endoscopy with multiple biopsies to look for changes (dysplasia). Pathologists vary dramatically in their interpretation of Barrett's Metaplasia versus dysplasia and consensus is very difficult to achieve. The investigators propose a longitudinal study of subjects with confirmed Barrett's intestinal metaplasia without dysplasia to look for predictive factors for transformation to dysplasia or cancer. Potential biomarkers can be found in serum, plasma, urine, frozen or fixed Barrett's and Normal esophageal mucosa. In addition, the investigators are testing a brushing technique from CDx, Inc. for predictive factors. Subjects must have pathologically confirmed Barrett's intestinal metaplasia without history of dysplasia to be on this longitudinal study.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 255 participants |
| Start Date | 2007-10 |
What the finished NCT00844077 record still lists
NCT00844077 is an observational study that tracks outcomes without assigning an intervention. The registered 255 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT00844077 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00844077 about?
NCT00844077 is a clinical study titled "Preliminary Longitudinal Validation of Biomarkers Predictive of Barrett's Esophagus". Barrett's esophagus can progress to esophageal cancer, but it doesn't always. Current treatment is frequent surveillance via upper endoscopy with multiple biopsies to look for changes (dysplasia). Pathologists vary dramatically in their interpretation of Barrett's Metaplasia versus dysplasia and con...
What is the current status of trial NCT00844077?
This trial is currently completed. The enrollment target is 255 participants. The study started on 2007-10.
Who is sponsoring clinical trial NCT00844077?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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