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NCT00843947 · ClinicalTrials.gov registry record · Phase 2
Reduced Intensity Stem Cell Transplantation (RIST) for Patients With Hematological Malignancies Conditioned With Fludarabine and Busulfan
A Phase 2 study, sponsored by University of California, Davis.
- Completed
- Registry status
- Phase 2
- Development phase
- 8
- Enrollment target
NCT00843947: Completed Phase 2 study, sponsored by University of California, Davis.
NCT00843947 is a Phase 2 study that has completed, run by University of California, Davis. The registered enrollment target is 8 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00843947, a Phase 2 study, has completed, sponsored by University of California, Davis.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 8 participants
- Enrollment target
Study Summary
This is a Phase II trial designed to evaluate the efficacy and toxicity of RIST, conditioned with fludarabine and busulfan, using G-CSF mobilized PBSC from an HLA-matched sibling or an unrelated volunteer donor. The primary endpoint of this study is day 100 TRM (Treatment Related Mortality). Secondary endpoints include response, engraftment times, acute and chronic GVHD, chimerism, toxicities, progression-free survival and overall survival. Objectives * To assess the efficacy and toxicity of Reduced Intensity Transplant (RIST) for patients with hematological malignancies, conditioned with fludarabine (Fludara®) and busulfan intravenous (Busulfex™). * To evaluate progression-free survival and overall survival. * To determine donor chimerism. * To assess the risk of acute and chronic graft versus host disease (GVHD).
Interventions
- PROCEDURE Reduced Intensity Stem Cell Transplantation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2007-06 |
| Est. Completion | 2013-11 |
| Phase | Phase 2 |
What the finished NCT00843947 record still lists
NCT00843947 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 1 intervention - of which Reduced Intensity Stem Cell Transplantation is the first listed.
NCT00843947 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00843947 about?
NCT00843947 is a clinical study titled "Reduced Intensity Stem Cell Transplantation (RIST) for Patients With Hematological Malignancies Conditioned With Fludarabine and Busulfan". This is a Phase II trial designed to evaluate the efficacy and toxicity of RIST, conditioned with fludarabine and busulfan, using G-CSF mobilized PBSC from an HLA-matched sibling or an unrelated volunteer donor. The primary endpoint of this study is day 100 TRM (Treatment Related Mortality). Seconda...
What is the current status of trial NCT00843947?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 8 participants. The study started on 2007-06. Estimated completion is 2013-11.
What interventions are being tested in trial NCT00843947?
The interventions under investigation include: Reduced Intensity Stem Cell Transplantation (PROCEDURE).
Who is sponsoring clinical trial NCT00843947?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00843947's enrollment target sits among peer trials
8 1990th of 2000 higher than 5 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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