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NCT00842400 · ClinicalTrials.gov registry record · Phase 1
A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.
A Phase 1 study, sponsored by VIVUS.
- Completed
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT00842400: Completed Phase 1 study, sponsored by VIVUS.
NCT00842400 is a Phase 1 study that has completed, run by VIVUS. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00842400, a Phase 1 study, has completed, sponsored by VIVUS.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purposes of this study are to: * Find out how much of the study drugs are in the blood of healthy subjects after taking multiple doses of VI-0521, metformin and sitagliptan. * Determine the effect of probenecid on the amount of VI-0521 in the blood of healthy subjects after taking multiple doses. * Find out how much topiramate is in the semen of healthy male subjects after taking multiple doses.
Interventions
- DRUG Metformin, VI-0521, Sitagliptan, Probenecid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2009-02 |
| Est. Completion | 2009-04 |
| Phase | Phase 1 |
What the finished NCT00842400 record still lists
NCT00842400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).
The record links to 0 conditions, and to 1 intervention - of which Metformin, VI-0521, Sitagliptan, Probenecid is the first listed.
NCT00842400 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00842400 about?
NCT00842400 is a clinical study titled "A Drug Interaction Study of VI-0521 With Metformin, Sitagliptan and Probenecid in Healthy Subjects.". The purposes of this study are to: * Find out how much of the study drugs are in the blood of healthy subjects after taking multiple doses of VI-0521, metformin and sitagliptan. * Determine the effect of probenecid on the amount of VI-0521 in the blood of healthy subjects after taking multiple dose...
What is the current status of trial NCT00842400?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2009-02. Estimated completion is 2009-04.
What interventions are being tested in trial NCT00842400?
The interventions under investigation include: Metformin, VI-0521, Sitagliptan, Probenecid (DRUG).
Who is sponsoring clinical trial NCT00842400?
This trial is sponsored by VIVUS, which has 35 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00842400's enrollment target sits among peer trials
20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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