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NCT00835289 · ClinicalTrials.gov registry record · NA
The Chronic Obstructive Pulmonary Disease Fish Oil Pilot Trial
A NA study, sponsored by Columbia University.
- Completed
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT00835289 is a NA study that has completed, run by Columbia University. The registered enrollment target is 40 participants.
The verdict
NCT00835289, a NA study, has completed, sponsored by Columbia University.
- COMPLETED
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the United States. Unlike the other leading causes of death, no medical therapies currently available improve the course of disease or affect survival in COPD. Recent investigations suggest that endothelial dysfunction and chronic inflammation is fundamental to COPD. Fish oil intake improves endothelial dysfunction and lowers levels of inflammatory intermediaries which may be important in the development of COPD. The Chronic Obstructive Pulmonary Disease Fish Oil (COD-Fish) Pilot Trial will enroll 40-45 participants with COPD. These participants will be randomized to receive omega-3 polyunsaturated fatty acid supplementation (PUFA) or placebo (containing corn oil). All participants will perform a number of noninvasive tests (including flow-mediated dilation (FMD) and pulmonary function testing) at study entry as well as every two months for a total of six months. Thirty participants who agree to it will undergo a separate procedure to collect cells from inside a forearm vein for analysis to be compared to 30 controls. The main purpose of this trial is to examine the effect of PUFA on endothelial function as measured by change in FMD in patients with COPD. We hypothesize that in subjects with COPD, treatment with PUFA will increase FMD.
Interventions
- OTHER Placebo
- DIETARY_SUPPLEMENT n-3 polyunsaturated fatty acids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2009-03 |
| Est. Completion | 2013-08 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00835289
The ClinicalTrials.gov registry entry for NCT00835289 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Columbia University, which has 958 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT00835289 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00835289 about?
NCT00835289 is a clinical study titled "The Chronic Obstructive Pulmonary Disease Fish Oil Pilot Trial". Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the United States. Unlike the other leading causes of death, no medical therapies currently available improve the course of disease or affect survival in COPD. Recent investigations suggest that endothelia...
What is the current status of trial NCT00835289?
This trial is currently completed. It is a NA study. The enrollment target is 40 participants. The study started on 2009-03. Estimated completion is 2013-08.
What interventions are being tested in trial NCT00835289?
The interventions under investigation include: Placebo (OTHER), n-3 polyunsaturated fatty acids (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT00835289?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
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