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NCT00817999 · ClinicalTrials.gov registry record · Phase 4
The Impact of Grapefruit Juice on the Response to Clopidogrel
A Phase 4 study, sponsored by Creighton University.
- Completed
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
NCT00817999: Completed Phase 4 study, sponsored by Creighton University.
NCT00817999 is a Phase 4 study that has completed, run by Creighton University. The registered enrollment target is 32 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00817999, a Phase 4 study, has completed, sponsored by Creighton University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
Study Summary
This study will measure the percentage of platelet aggregation inhibition with a loading dose of clopidogrel (300 mg) using the VerifyNow Assay System in healthy volunteers who have drank 11 oz of grapefruit juice. It will also measure the percentage of platelet aggregation inhibition with a maintenance dose of clopidogrel (75 mg/day) using the VerifyNow Assay System in healthy volunteers who have drank 11 oz grapefruit juice daily.
Primary Outcome
% platelet inhibition measured by Verify Now
Interventions
- DIETARY_SUPPLEMENT Grapefruit juice
- DRUG Clopidogrel 75 mg/day
- DRUG Clopidogrel 300 mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2008-11 |
| Est. Completion | 2011-07 |
| Phase | Phase 4 |
What the finished NCT00817999 record still lists
NCT00817999 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (94% lower).
The record links to 0 conditions, and to 3 interventions - of which Grapefruit juice is the first listed.
NCT00817999 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00817999 about?
NCT00817999 is a clinical study titled "The Impact of Grapefruit Juice on the Response to Clopidogrel". This study will measure the percentage of platelet aggregation inhibition with a loading dose of clopidogrel (300 mg) using the VerifyNow Assay System in healthy volunteers who have drank 11 oz of grapefruit juice. It will also measure the percentage of platelet aggregation inhibition with a mainten...
What is the current status of trial NCT00817999?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2008-11. Estimated completion is 2011-07.
What interventions are being tested in trial NCT00817999?
The interventions under investigation include: Grapefruit juice (DIETARY_SUPPLEMENT), Clopidogrel 75 mg/day (DRUG), Clopidogrel 300 mg (DRUG).
Who is sponsoring clinical trial NCT00817999?
This trial is sponsored by Creighton University, which has 98 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00817999's enrollment target sits among peer trials
32 1534th of 2000 higher than 457 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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