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NCT00815958 · ClinicalTrials.gov registry record · NA
Embolic Events Detected During Total Knee Arthroplasty With the Use of RIA (Reamer-Irrigator-Aspirator)
A NA study, sponsored by Ohio State University.
- Terminated
- Registry status
- NA
- Development phase
- 6
- Enrollment target
NCT00815958: Clinical Trial NA study, sponsored by Ohio State University.
NCT00815958 is a NA study that was terminated before completion, run by Ohio State University. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00815958, a NA study, was terminated before completion, sponsored by Ohio State University.
- TERMINATED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
Study Summary
The embolisation of fat and bone marrow during long bone instrumentation is a well-known complication of major joint replacement surgery. Clinically significant venous thromboembolic disease, cardiopulmonary dysfunction,cerebral emboli, and death have all been described. Because the intravasation of medullary contents is caused by increased pressure during canal instrumentation, the use of the Synthes RIA (Reamer-Irrigator-Aspirator), a negative pressure-irrigated high-speed reamer, may result in a lower incidence of embolism. This controlled clinical trial will evaluate the utility of the RIA in reducing the frequency and severity of embolic events as detected by intraoperative transesophageal echocardiography (TEE) and transcranial Doppler (TCD) during total knee arthroplasty (TKA) surgery.
Interventions
- PROCEDURE Reaming with Synthes RIA (Reamer-Irrigator-Aspirator)
- PROCEDURE Reaming with conventional reamer
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2007-12 |
| Est. Completion | 2009-03 |
| Phase | NA |
Why NCT00815958 stopped before completion
NCT00815958 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 2 interventions - of which Reaming with Synthes RIA (Reamer-Irrigator-Aspirator) is the first listed.
NCT00815958 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00815958 about?
NCT00815958 is a clinical study titled "Embolic Events Detected During Total Knee Arthroplasty With the Use of RIA (Reamer-Irrigator-Aspirator)". The embolisation of fat and bone marrow during long bone instrumentation is a well-known complication of major joint replacement surgery. Clinically significant venous thromboembolic disease, cardiopulmonary dysfunction,cerebral emboli, and death have all been described. Because the intravasation of...
What is the current status of trial NCT00815958?
This trial is currently terminated. It is a NA study. The enrollment target is 6 participants. The study started on 2007-12. Estimated completion is 2009-03.
What interventions are being tested in trial NCT00815958?
The interventions under investigation include: Reaming with Synthes RIA (Reamer-Irrigator-Aspirator) (PROCEDURE), Reaming with conventional reamer (PROCEDURE).
Who is sponsoring clinical trial NCT00815958?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00815958's enrollment target sits among peer trials
6 1983rd of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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