Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00813813 · ClinicalTrials.gov registry record · Phase 1
Intradiscal rhGDF-5 Phase I/II Clinical Trial
A Phase 1 study, sponsored by DePuy Spine.
- Completed
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT00813813: Completed Phase 1 study, sponsored by DePuy Spine.
NCT00813813 is a Phase 1 study that has completed, run by DePuy Spine. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00813813, a Phase 1 study, has completed, sponsored by DePuy Spine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
Study to show the effectiveness and safety of a single injection of rhGDF5 into a degenerating single spinal disc in treating lumbar level degenerative disc disease
Primary Outcome
Neurological Assessment for Motor Function and Reflexes/Sensory- Number of patients with Clinically Significant Abnormal results at 12 months. For Motor Function, Clinically Significant Abnormal results are determined by the surgeon investigator and are further classified by grade: 0= No Movement, 1= Flicker/trace of contraction, 2=Active movement when gravity removed, 3= Active movement against gravity, 4= Active Movement against gravity and resistance. For Reflexes/Sensory, Clinically Signif
Interventions
- DRUG Intradiscal rhGDF-5
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2008-06 |
| Est. Completion | 2013-06 |
| Phase | Phase 1 |
What the finished NCT00813813 record still lists
NCT00813813 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 1 intervention - of which Intradiscal rhGDF-5 is the first listed.
NCT00813813 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00813813 about?
NCT00813813 is a clinical study titled "Intradiscal rhGDF-5 Phase I/II Clinical Trial". Study to show the effectiveness and safety of a single injection of rhGDF5 into a degenerating single spinal disc in treating lumbar level degenerative disc disease
What is the current status of trial NCT00813813?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2008-06. Estimated completion is 2013-06.
What interventions are being tested in trial NCT00813813?
The interventions under investigation include: Intradiscal rhGDF-5 (DRUG).
Who is sponsoring clinical trial NCT00813813?
This trial is sponsored by DePuy Spine, which has 5 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00813813's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02445781 · 32 participants · Early Phase 1
Differing Levels of Hypoglycemia
- NCT02792270 · 32 participants · NA
Caloric Restriction In Sarcoma Patients Treated With Pre-Operative RT
- NCT03068910 · 32 participants · Early Phase 1
Hyperandrogenemia and Altered Day-night LH Pulse Patterns
- NCT03208868 · 32 participants · NA
Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia