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NCT00806390 · ClinicalTrials.gov registry record · Phase 4
Prevention of Anthracycline or Trastuzumab Induced Cardiomyopathy by Metoprolol
A Phase 4 study, sponsored by University of Maryland, Baltimore.
- Terminated
- Registry status
- Phase 4
- Development phase
- 15
- Enrollment target
NCT00806390: Clinical Trial Phase 4 study, sponsored by University of Maryland, Baltimore.
NCT00806390 is a Phase 4 study that was terminated before completion, run by University of Maryland, Baltimore. The registered enrollment target is 15 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00806390, a Phase 4 study, was terminated before completion, sponsored by University of Maryland, Baltimore.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 15 participants
- Enrollment target
Study Summary
The primary objective of this study is to investigate whether giving prophylactic metoprolol prior to and during anthracycline or trastuzumab therapy will decrease the incidence of anthracycline-induced cardiomyopathy. Patients are randomized to receive metoprolol or no treatment prior to anthracycline or trastuzumab treatment. The ejection fraction, as measured by nuclear ventriculography is measured before and after treatment.
Primary Outcome
Because of the inability to enroll an adequate number of patients, (only 15 out of a planned 50) no data analysis was collected or performed.
Interventions
- DRUG Metoprolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2008-07 |
| Est. Completion | 2012-06 |
| Phase | Phase 4 |
Why NCT00806390 stopped before completion
NCT00806390 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Metoprolol is the first listed.
NCT00806390 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00806390 about?
NCT00806390 is a clinical study titled "Prevention of Anthracycline or Trastuzumab Induced Cardiomyopathy by Metoprolol". The primary objective of this study is to investigate whether giving prophylactic metoprolol prior to and during anthracycline or trastuzumab therapy will decrease the incidence of anthracycline-induced cardiomyopathy. Patients are randomized to receive metoprolol or no treatment prior to anthracycl...
What is the current status of trial NCT00806390?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 15 participants. The study started on 2008-07. Estimated completion is 2012-06.
What interventions are being tested in trial NCT00806390?
The interventions under investigation include: Metoprolol (DRUG).
Who is sponsoring clinical trial NCT00806390?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00806390's enrollment target sits among peer trials
15 1880th of 2000 higher than 100 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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