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NCT00798135 · ClinicalTrials.gov registry record · NA
A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer
A NA study, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 13
- Enrollment target
NCT00798135: Completed NA study, sponsored by Indiana University.
NCT00798135 is a NA study that has completed, run by Indiana University. The registered enrollment target is 13 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00798135, a NA study, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 13 participants
- Enrollment target
Study Summary
Cancer cells need to be able to make new blood vessels in order to keep growing. This is called angiogenesis. In a laboratory setting, the drug itraconazole was shown to help stop the growth of new blood vessels (anti-angiogenesis). It is hoped that itraconazole will prevent new blood vessels from forming in humans too. The purpose of this study is to look at how the body processes and breaks down itraconazole (called pharmacokinetics). This study will also measure markers in your blood to see if itraconazole stops new blood vessels from forming. The safety of itraconazole will also be tested to see what effects (good and bad) it has on you and your breast cancer.
Primary Outcome
To determine the pharmacokinetics (PK) of oral itraconazole in patients with MBC by measuring mean trough plasma levels at steady state at weeks 2 and 4.
Interventions
- DRUG itraconazole
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2008-11 |
| Est. Completion | 2012-03 |
| Phase | NA |
What the finished NCT00798135 record still lists
NCT00798135 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which itraconazole is the first listed.
NCT00798135 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00798135 about?
NCT00798135 is a clinical study titled "A Pilot Trial of Itraconazole Pharmacokinetics in Patients With Metastatic Breast Cancer". Cancer cells need to be able to make new blood vessels in order to keep growing. This is called angiogenesis. In a laboratory setting, the drug itraconazole was shown to help stop the growth of new blood vessels (anti-angiogenesis). It is hoped that itraconazole will prevent new blood vessels from f...
What is the current status of trial NCT00798135?
This trial is currently completed. It is a NA study. The enrollment target is 13 participants. The study started on 2008-11. Estimated completion is 2012-03.
What interventions are being tested in trial NCT00798135?
The interventions under investigation include: itraconazole (DRUG).
Who is sponsoring clinical trial NCT00798135?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00798135's enrollment target sits among peer trials
13 1911th of 2000 higher than 88 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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