Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00792233 · ClinicalTrials.gov registry record · Phase 4

Determining Predictors of Safe Discontinuation of Anti-TNF Treatment in JIA

A Phase 4 study, sponsored by Children's Hospital Medical Center, Cincinnati.

Completed
Registry status
Phase 4
Development phase
137
Enrollment target

NCT00792233: Completed Phase 4 study, sponsored by Children's Hospital Medical Center, Cincinnati.

NCT00792233 is a Phase 4 study that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 137 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (74% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00792233, a Phase 4 study, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.

COMPLETED
Registry status
Phase 4
Development phase
137 participants
Enrollment target

Study Summary

Polyarticular juvenile idiopathic arthritis (Poly JIA) is a form of juvenile arthritis, which is a chronic disease affecting approximately 250,000 people younger than 16 years of age. Poly JIA can be treated with anti-tumor necrosis factor (anti-TNF), a type of medication that is often effective but also has some toxic side effects and is expensive. Among those with poly JIA who are effectively treated with anti-TNF, some can remain healthy off the medication, but some begin to feel the effects of their disease again once the medication is stopped. This study will attempt to find whether certain tests or signs can predict which people with poly JIA can safely stop their anti-TNF medications.

Interventions

  • OTHER Withdrawal of anti-TNF therapy

Trial Details

FieldValue
Enrollment Target 137 participants
Start Date 2009-06
Est. Completion 2015-10
Phase Phase 4

What the finished NCT00792233 record still lists

NCT00792233 is an interventional study that assigns participants to a tested intervention. The registered 137 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (74% lower).

The record links to 0 conditions, and to 1 intervention - of which Withdrawal of anti-TNF therapy is the first listed.

NCT00792233 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00792233 about?

NCT00792233 is a clinical study titled "Determining Predictors of Safe Discontinuation of Anti-TNF Treatment in JIA". Polyarticular juvenile idiopathic arthritis (Poly JIA) is a form of juvenile arthritis, which is a chronic disease affecting approximately 250,000 people younger than 16 years of age. Poly JIA can be treated with anti-tumor necrosis factor (anti-TNF), a type of medication that is often effective but...

What is the current status of trial NCT00792233?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 137 participants. The study started on 2009-06. Estimated completion is 2015-10.

What interventions are being tested in trial NCT00792233?

The interventions under investigation include: Withdrawal of anti-TNF therapy (OTHER).

Who is sponsoring clinical trial NCT00792233?

This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00792233's enrollment target sits among peer trials

137 594th of 2000 higher than 1,405 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05091424 · 137 participants · Phase 1

    A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

  • NCT05655182 · 137 participants · Phase 1

    A Study of BLB-201 RSV Vaccine in Infants and Children

  • NCT06571669 · 137 participants · NA

    BOOM-IBD2 Pivotal Clinical Trial

  • NCT06644768 · 137 participants · Phase 1

    A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00792233, the US trial registry maintained by the National Library of Medicine. NCT00792233 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.