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NCT00786643 · ClinicalTrials.gov registry record · Phase 2
Study of Gamma Interfereon in Metastatic Colorectal Carcinoma
A Phase 2 study, sponsored by Accelerated Community Oncology Research Network.
- Completed
- Registry status
- Phase 2
- Development phase
- 48
- Enrollment target
NCT00786643: Completed Phase 2 study, sponsored by Accelerated Community Oncology Research Network.
NCT00786643 is a Phase 2 study that has completed, run by Accelerated Community Oncology Research Network. The registered enrollment target is 48 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00786643, a Phase 2 study, has completed, sponsored by Accelerated Community Oncology Research Network.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 48 participants
- Enrollment target
Study Summary
The purpose of this study is to evalute the response and toxicity of metastatic colorectal cancer patients to the regimen of gamma interferon added to bolus and infusional 5-fluorouracil and leucovorin (GFL) with or without bevacizumab.
Primary Outcome
BR is recorded from start of treatment until progressive disease (PD). Imaging was repeated by same technique after every 4 cycles of treatment. Response was evaluated per Response Evaluation Criteria In Solid Tumors (RECIST) guidelines version 1.0. Per RECIST v1.0 and CT scan: Complete Response (CR), disappearance of all target lesions; Partial Response (PR), \>=30% decrease in the sum of longest diameter of target lesions; Stable Disease (SD), neither sufficient shrinkage in sum of LD of targe
Interventions
- DRUG Bevacizumab
- DRUG 5-Fluorouracil
- DRUG Leucovorin (LV)
- DRUG Gamma-Interferon-1b (IFN-γ)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2006-02 |
| Est. Completion | 2010-03 |
| Phase | Phase 2 |
What the finished NCT00786643 record still lists
NCT00786643 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (64% lower).
The record links to 0 conditions, and to 4 interventions - of which Bevacizumab is the first listed.
NCT00786643 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00786643 about?
NCT00786643 is a clinical study titled "Study of Gamma Interfereon in Metastatic Colorectal Carcinoma". The purpose of this study is to evalute the response and toxicity of metastatic colorectal cancer patients to the regimen of gamma interferon added to bolus and infusional 5-fluorouracil and leucovorin (GFL) with or without bevacizumab.
What is the current status of trial NCT00786643?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 48 participants. The study started on 2006-02. Estimated completion is 2010-03.
What interventions are being tested in trial NCT00786643?
The interventions under investigation include: Bevacizumab (DRUG), 5-Fluorouracil (DRUG), Leucovorin (LV) (DRUG), Gamma-Interferon-1b (IFN-γ) (DRUG).
Who is sponsoring clinical trial NCT00786643?
This trial is sponsored by Accelerated Community Oncology Research Network, which has 16 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00786643's enrollment target sits among peer trials
48 1265th of 2000 higher than 718 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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