Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00782834 · ClinicalTrials.gov registry record · Phase 2

Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST)

A Phase 2 study, sponsored by Fox Chase Cancer Center.

Terminated
Registry status
Phase 2
Development phase
13
Enrollment target

NCT00782834: Clinical Trial Phase 2 study, sponsored by Fox Chase Cancer Center.

NCT00782834 is a Phase 2 study that was terminated before completion, run by Fox Chase Cancer Center. The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00782834, a Phase 2 study, was terminated before completion, sponsored by Fox Chase Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

This is a phase II study of Nilotinib for patients with advanced GIST that cannot be surgically removed. Patients are candidates for the study if their tumors have progressed on imatinib and sunitinib or if they were intolerant to these drugs. Patients may have received other investigational therapies as well. We are testing the benefit of nilotinib in advanced GIST looking at the length of time disease is controlled as well as the response of the disease to the drug.

Primary Outcome

Number of participants that demonstrate progression free survival at 6 months

Interventions

  • DRUG Nilotinib

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2008-07
Est. Completion 2009-10
Phase Phase 2
Fox Chase Cancer Center

183 total trials

Why NCT00782834 stopped before completion

NCT00782834 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which Nilotinib is the first listed.

NCT00782834 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00782834 about?

NCT00782834 is a clinical study titled "Nilotinib in Advanced Gastrointestinal Stromal Tumors (GIST)". This is a phase II study of Nilotinib for patients with advanced GIST that cannot be surgically removed. Patients are candidates for the study if their tumors have progressed on imatinib and sunitinib or if they were intolerant to these drugs. Patients may have received other investigational therapi...

What is the current status of trial NCT00782834?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2008-07. Estimated completion is 2009-10.

What interventions are being tested in trial NCT00782834?

The interventions under investigation include: Nilotinib (DRUG).

Who is sponsoring clinical trial NCT00782834?

This trial is sponsored by Fox Chase Cancer Center, which has 183 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00782834's enrollment target sits among peer trials

13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03125655 · 13 participants

    Regulation of Inflammatory Genes in Psoriasis

  • NCT03774446 · 13 participants · Phase 2

    Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

  • NCT03830151 · 13 participants · Phase 1

    Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

  • NCT04573231 · 13 participants · Phase 2

    Evaluation of PSMA in HER2- AR+ Metastatic Breast Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00782834, the US trial registry maintained by the National Library of Medicine. NCT00782834 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.