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NCT00780741 · ClinicalTrials.gov registry record · Phase 3

Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old

A Phase 3 study of Nasolacrimal Duct Obstruction, sponsored by Jaeb Center for Health Research.

Completed
Registry status
Phase 3
Development phase
220
Enrollment target
1
Study location

NCT00780741: Completed Phase 3 study of Nasolacrimal Duct Obstruction, sponsored by Jaeb Center for Health Research.

NCT00780741 is a Phase 3 study of Nasolacrimal Duct Obstruction that has completed, run by Jaeb Center for Health Research. The registered enrollment target is 220 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00780741, a Phase 3 study of Nasolacrimal Duct Obstruction, has completed, sponsored by Jaeb Center for Health Research.

COMPLETED
Registry status
Phase 3
Development phase
220 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is: To determine the cost-effectiveness of treating NLDO using immediate office probing compared with deferred probing in a facility setting. As part of the primary objective, the study will determine the proportion of eyes experiencing spontaneous resolution among subjects randomized to the deferred probing group. The secondary objectives are: 1. To determine the success proportion for eyes undergoing immediate office probing as an initial procedure. 2. To determine the success proportion for eyes undergoing deferred facility probing as an initial procedure.

Primary Outcome

Absence of three clinical signs of NLDO (epiphora, increased tear lake, and mucous discharge) upon masked examination at 18 months of age.

Interventions

  • PROCEDURE Immediate Office Probing
  • PROCEDURE Deferred Facility Probing

Study Locations (1)

Idaho

  • Intermountain Eye Centers - Boise

Trial Details

FieldValue
Enrollment Target 220 participants
Start Date 2008-10
Est. Completion 2012-01
Phase Phase 3
Jaeb Center for Health Research

119 total trials

What the finished NCT00780741 record still lists

NCT00780741 is an interventional study that assigns participants to a tested intervention. The registered 220 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (72% lower).

The record links to 1 condition, with Nasolacrimal Duct Obstruction appearing as the primary indexed condition, and to 2 interventions - of which Immediate Office Probing is the first listed.

NCT00780741 reports a single indexed study location in Idaho.

Frequently Asked Questions

What is clinical trial NCT00780741 about?

NCT00780741 is a clinical study titled "Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old". The purpose of this study is: To determine the cost-effectiveness of treating NLDO using immediate office probing compared with deferred probing in a facility setting. As part of the primary objective, the study will determine the proportion of eyes experiencing spontaneous resolution among subject...

What is the current status of trial NCT00780741?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 220 participants. The study started on 2008-10. Estimated completion is 2012-01.

What conditions does trial NCT00780741 study?

This clinical trial studies the following conditions: Nasolacrimal Duct Obstruction.

What interventions are being tested in trial NCT00780741?

The interventions under investigation include: Immediate Office Probing (PROCEDURE), Deferred Facility Probing (PROCEDURE).

Who is sponsoring clinical trial NCT00780741?

This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00780741 being conducted?

This trial has 1 study location across Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Nasolacrimal Duct Obstruction

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00780741's enrollment target sits among peer trials

220 1318th of 2000 higher than 672 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00780741, the US trial registry maintained by the National Library of Medicine. NCT00780741 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.