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NCT00778856 · ClinicalTrials.gov registry record · NA

Hand Transplantation for the Reconstruction of Below the Elbow Amputations

A NA study, sponsored by Emory University.

Terminated
Registry status
NA
Development phase
19
Enrollment target

NCT00778856: Clinical Trial NA study, sponsored by Emory University.

NCT00778856 is a NA study that was terminated before completion, run by Emory University. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00778856, a NA study, was terminated before completion, sponsored by Emory University.

TERMINATED
Registry status
NA
Development phase
19 participants
Enrollment target

Study Summary

Organ transplantation has become the treatment of choice for most patients suffering end stage diseases of the kidney, pancreas, liver, heart or lung. Vascularized Composite Allotransplantation (VCA) {a.k.a. composite tissue allotransplantation} is the term used to describe transplantation of multiple tissues (skin, muscle, bone, cartilage, nerve, tendon, vessel) as a functional unit (e.g. hand). Several recent advances in clinical organ transplant immunosuppression and experimental limb VCA have now made it feasible to consider clinical VCA for the functional restoration of patients with loss of one or both hands. This protocol facilitates the development of limb VCA at the Atlanta Veterans Affairs Medical Center (VAMC) and at Emory University for patients with below the elbow amputations. It will evaluate the patients' use of transplanted limb(s) in activities of daily living and compare the function of the transplanted hand to the function with their previous prosthesis. Patients with below the elbow amputations will be enrolled. Donor tissue will be recovered from deceased donors following the guidelines of and in cooperation with the regional Organ Procurement Organization. The transplantation procedure and postoperative care will be performed using the standard technique for limb replantation. Patients will receive standard immunosuppressive regimen. Rejections will be treated in keeping with experience from the solid organ transplant experience. Graft failure will be treated with allograft amputation.

Interventions

  • PROCEDURE Hand transplantation

Trial Details

FieldValue
Enrollment Target 19 participants
Start Date 2008-09
Est. Completion 2013-03
Phase NA
Emory University

1,208 total trials

Why NCT00778856 stopped before completion

NCT00778856 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Hand transplantation is the first listed.

NCT00778856 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00778856 about?

NCT00778856 is a clinical study titled "Hand Transplantation for the Reconstruction of Below the Elbow Amputations". Organ transplantation has become the treatment of choice for most patients suffering end stage diseases of the kidney, pancreas, liver, heart or lung. Vascularized Composite Allotransplantation (VCA) {a.k.a. composite tissue allotransplantation} is the term used to describe transplantation of multi...

What is the current status of trial NCT00778856?

This trial is currently terminated. It is a NA study. The enrollment target is 19 participants. The study started on 2008-09. Estimated completion is 2013-03.

What interventions are being tested in trial NCT00778856?

The interventions under investigation include: Hand transplantation (PROCEDURE).

Who is sponsoring clinical trial NCT00778856?

This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00778856's enrollment target sits among peer trials

19 1861st of 2000 higher than 138 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00778856, the US trial registry maintained by the National Library of Medicine. NCT00778856 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.