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NCT00771901 · ClinicalTrials.gov registry record · NA
Effect of Endoplasmic Reticulum Stress on Metabolic Function
A NA study, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- NA
- Development phase
- 101
- Enrollment target
NCT00771901 is a NA study that has completed, run by Washington University School of Medicine. The registered enrollment target is 101 participants.
The verdict
NCT00771901, a NA study, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- NA
- Development phase
- 101 participants
- Enrollment target
Study Summary
Normally, the hormone insulin works to help keep blood sugar normal. However, as a person gains weight, insulin does not work as well and blood sugar tends to be a little higher than normal. This is called "insulin resistance". Two investigational drugs (not approved by the Food and Drug Administration) for the treatment of high lipid levels or insulin resistance are being examined in this study: one drug is called tauroursodeoxycholic acid (TUDCA), the other is called sodium phenylbutyrate (PBA). This study is designed to test if TUDCA and/or PBA is effective in people who are obese with insulin resistance and high lipids. We hypothesize that pharmacologically-induced decreases in ER stress will improve insulin action and hepatic lipid metabolism in obese subjects.
Interventions
- OTHER placebo
- DRUG sodium phenylbutyrate
- DRUG tauroursodeoxycholic acid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 101 participants |
| Start Date | 2008-02 |
| Est. Completion | 2014-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00771901
The ClinicalTrials.gov registry entry for NCT00771901 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 101 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which placebo is the first listed.
NCT00771901 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00771901 about?
NCT00771901 is a clinical study titled "Effect of Endoplasmic Reticulum Stress on Metabolic Function". Normally, the hormone insulin works to help keep blood sugar normal. However, as a person gains weight, insulin does not work as well and blood sugar tends to be a little higher than normal. This is called "insulin resistance". Two investigational drugs (not approved by the Food and Drug Administra...
What is the current status of trial NCT00771901?
This trial is currently completed. It is a NA study. The enrollment target is 101 participants. The study started on 2008-02. Estimated completion is 2014-12.
What interventions are being tested in trial NCT00771901?
The interventions under investigation include: placebo (OTHER), sodium phenylbutyrate (DRUG), tauroursodeoxycholic acid (DRUG).
Who is sponsoring clinical trial NCT00771901?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
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