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NCT00770757 · ClinicalTrials.gov registry record · Phase 2

CC-4047 (Pomalidomide) for Graft vs. Host Disease

A Phase 2 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 2
Development phase
13
Enrollment target

NCT00770757: Completed Phase 2 study, sponsored by Washington University School of Medicine.

NCT00770757 is a Phase 2 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 13 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00770757, a Phase 2 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

This study will test the safety and effectiveness CC-4047 (pomalidomide) in patients with advanced, steroid refractory graft-versus-host disease.

Primary Outcome

* CR is defined as complete resolution in all of signs and symptoms at all affected organs and tissues * PR is defined as improvement in greater than or equal to 1 organ/tissue with no progression in any other affected organ/tissue * Improvement in chronic GvHD symptoms less than what meets the definition of a PR is defined as other * Progressive disease is defined as failure of therapy to control chronic GvHD despite increasing the dose of primary therapy or adding second line treatments * No r

Interventions

  • DRUG CC-4047

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2009-02
Est. Completion 2011-10
Phase Phase 2

What the finished NCT00770757 record still lists

NCT00770757 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 13 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which CC-4047 is the first listed.

NCT00770757 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00770757 about?

NCT00770757 is a clinical study titled "CC-4047 (Pomalidomide) for Graft vs. Host Disease". This study will test the safety and effectiveness CC-4047 (pomalidomide) in patients with advanced, steroid refractory graft-versus-host disease.

What is the current status of trial NCT00770757?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2009-02. Estimated completion is 2011-10.

What interventions are being tested in trial NCT00770757?

The interventions under investigation include: CC-4047 (DRUG).

Who is sponsoring clinical trial NCT00770757?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00770757's enrollment target sits among peer trials

13 1947th of 2000 higher than 53 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00770757, the US trial registry maintained by the National Library of Medicine. NCT00770757 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.