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NCT00767767 · ClinicalTrials.gov registry record · NA
The Effect of Intravenous Anesthetics on Fear Learning and Memory
A NA study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- NA
- Development phase
- 67
- Enrollment target
NCT00767767 is a NA study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 67 participants.
The verdict
NCT00767767, a NA study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- NA
- Development phase
- 67 participants
- Enrollment target
Study Summary
People often develop fearful responses to things, but have no conscious control over the fear. This is a basic form of unconscious memory, called "fear conditioning." Intravenous anesthetic drugs have remarkable effects on conscious memory, but it is unknown whether they have similar effects on these unconscious fear memories. To address this question, the investigators will study 114 healthy adult volunteer subjects. The subject is given a very low dose of an anesthetic drug intravenously (i.e. through the bloodstream). The dose is so low that the subject might not even be able tell if they are getting the drug. While they are receiving the drug, the subject will perform a series of memory tests and a fear conditioning experiment, which are set up like a very simple computer game. To create the "fear response", subjects will occasionally receive a mildly uncomfortable shock to their arm. The subject is able to determine the highest level of shock that they will receive. The investigators are doing this study because the investigators wish to know exactly how the drugs affect the way people process fear and emotion. This knowledge might one day be used in the treatment of some psychiatric disorders.
Interventions
- DRUG Placebos
- DRUG Propofol 0.45mcg/mL
- DRUG Propofol 0.90mcg/mL
- DRUG Thiopental 1.5mcg/mL
- DRUG Thiopental 3mcg/mL
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 67 participants |
| Start Date | 2008-10 |
| Est. Completion | 2011-05 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00767767
The ClinicalTrials.gov registry entry for NCT00767767 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 67 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Weill Medical College of Cornell University, which has 701 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Placebos is the first listed.
NCT00767767 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00767767 about?
NCT00767767 is a clinical study titled "The Effect of Intravenous Anesthetics on Fear Learning and Memory". People often develop fearful responses to things, but have no conscious control over the fear. This is a basic form of unconscious memory, called "fear conditioning." Intravenous anesthetic drugs have remarkable effects on conscious memory, but it is unknown whether they have similar effects on thes...
What is the current status of trial NCT00767767?
This trial is currently completed. It is a NA study. The enrollment target is 67 participants. The study started on 2008-10. Estimated completion is 2011-05.
What interventions are being tested in trial NCT00767767?
The interventions under investigation include: Placebos (DRUG), Propofol 0.45mcg/mL (DRUG), Propofol 0.90mcg/mL (DRUG), Thiopental 1.5mcg/mL (DRUG), Thiopental 3mcg/mL (DRUG).
Who is sponsoring clinical trial NCT00767767?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
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